When is a hydrophobic gate not a hydrophobic gate?

<p>The flux of ions through a channel is most commonly regulated by changes that result in steric occlusion of its pore. However, ion permeation can also be prevented by formation of a desolvation barrier created by hydrophobic residues that line the pore. As a result of relatively minor struc...

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Main Authors: Seiferth, D, Biggin, PC, Tucker, SJ
格式: Journal article
语言:English
出版: Rockefeller University Press 2022