Enhanced efficacy in drug-resistant cancer cells through synergistic nanoparticle mediated delivery of cisplatin and decitabine

Enhanced efficacy in drug-resistant cancer cells through synergistic nanoparticle mediated delivery of cisplatin and decitabine

There are several limitations with monodrug cancer therapy, including poor bioavailability, rapid clearance and drug resistance. Combination therapy addresses these by exploiting synergism between different drugs against cancer cells. In particular, the combination of epigenetic therapies with conve...

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Bibliographic Details
Main Authors:	Parhizkar, M, Reardon, PJT, Harker, AH, Browning, RJ, Stride, E, Pedley, RB, Knowles, JC, Edirisinghe, M
Format:	Journal article
Language:	English
Published:	Royal Society of Chemistry (RSC) 2020

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