Muscle acetylcholine receptor conversion into chloride conductance at positive potentials by a single mutation

Muscle acetylcholine receptor conversion into chloride conductance at positive potentials by a single mutation

Charge selectivity forms the basis of cellular excitation or inhibition by Cys-loop ligand-gated ion channels (LGICs), and is essential for physiological receptor function. There are no reports of naturally occurring mutations in LGICs associated with the conversion of charge selectivity. Here, we r...

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Bibliografiske detaljer
Main Authors:	Cetin, H, Epstein, M, Liu, W, Maxwell, S, Rodriguez Cruz, P, Cossins, J, Vincent, A, Webster, R, Biggin, P, Beeson, D
Format:	Journal article
Sprog:	English
Udgivet:	National Academy of Sciences 2019

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