DNA Replication and associated repair pathways are involved in the mutagenesis of methylated cytosine
Transitions of cytosine to thymine in CpG dinucleotides are the most frequent type of mutations observed in cancer. This increased mutability is commonly explained by the presence of 5-methylcytosine (5mC) and its spontaneous hydrolytic deamination into thymine. Here, we describe observations that q...
| Main Authors: | , , , |
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| 格式: | Journal article |
| 出版: |
Elsevier
2017
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