Evidence of cis-acting regulatory variation in PTPN22 in patients with rheumatoid arthritis.

OBJECTIVES: To assess whether there are cis-regulatory polymorphisms that regulate protein tyrosine phosphatase, non-receptor type 22 (PTPN22) expression in rheumatoid arthritis (RA). METHODS: RNA was extracted from positively selected CD56+, CD8+, and CD4+ mononuclear cells and the 'residual&...

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Bibliographic Details
Main Authors: Harrison, P, Southam, L, Chapman, K, Locklin, R, Sabokbar, A, Wordsworth, B, Pointon, J
Format: Journal article
Language:English
Published: 2012

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