T cell depletion by exposure to Campath-1G in vitro prevents graft-versus-host disease.
Campath-1G is an immunosuppressive monoclonal antibody directed against human lymphocytes. Its effectiveness in preventing graft-versus-host disease (GVHD) by simple opsonisation of bone marrow T-cells has been studied in 36 consecutive allografts: in 17 for leukaemia, one for essential thrombocytos...
Main Authors: | Jacobs, P, Wood, L, Fullard, L, Waldmann, H, Hale, G |
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Format: | Journal article |
Language: | English |
Published: |
1994
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