Early and nonreversible decrease of CD161++ /MAIT cells in HIV infection.
HIV infection is associated with immune dysfunction, perturbation of immune-cell subsets and opportunistic infections. CD161++ CD8+ T cells are a tissue-infiltrating population that produce IL17A, IL22, IFN, and TNFα, cytokines important in mucosal immunity. In adults they dominantly express the sem...
Main Authors: | Cosgrove, C, Ussher, J, Rauch, A, Gärtner, K, Kurioka, A, Hühn, M, Adelmann, K, Kang, Y, Fergusson, JR, Simmonds, P, Goulder, P, Hansen, T, Fox, J, Günthard, H, Khanna, N, Powrie, F, Steel, A, Gazzard, B, Phillips, R, Frater, J, Uhlig, H, Klenerman, P |
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Format: | Journal article |
Language: | English |
Published: |
2013
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