Early and nonreversible decrease of CD161++ /MAIT cells in HIV infection.

Early and nonreversible decrease of CD161++ /MAIT cells in HIV infection.

HIV infection is associated with immune dysfunction, perturbation of immune-cell subsets and opportunistic infections. CD161++ CD8+ T cells are a tissue-infiltrating population that produce IL17A, IL22, IFN, and TNFα, cytokines important in mucosal immunity. In adults they dominantly express the sem...

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Hlavní autoři: Cosgrove, C, Ussher, J, Rauch, A, Gärtner, K, Kurioka, A, Hühn, M, Adelmann, K, Kang, Y, Fergusson, JR, Simmonds, P, Goulder, P, Hansen, T, Fox, J, Günthard, H, Khanna, N, Powrie, F, Steel, A, Gazzard, B, Phillips, R, Frater, J, Uhlig, H, Klenerman, P
Médium: Journal article
Jazyk:English
Vydáno: 2013

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