Combinatorial HLA-peptide bead libraries for high throughput identification of CD8+ T cell specificity

Combinatorial HLA-peptide bead libraries for high throughput identification of CD8+ T cell specificity

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Comprehensive antigenic characterization of a T cell population of unknown specificity is challenging. Existing MHC class I expression systems are limited by the practical difficulty of probing cell populations with an MHC class I peptide library and the cross-reactivity of T cells that are able to...

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Dettagli Bibliografici
Autori principali:	Pan, X, Huang, L, Dong, T, Peng, Y, Cerundolo, V, McGowan, S, Ogg, G
Natura:	Journal article
Lingua:	English
Pubblicazione:	2014

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