DNA damage remodels the MITF interactome to increase melanoma genomic instability
Since genome instability can drive cancer initiation and progression, cells have evolved highly effective and ubiquitous DNA damage response (DDR) programs. However, some cells (for example, in skin) are normally exposed to high levels of DNA-damaging agents. Whether such high-risk cells possess lin...
Հիմնական հեղինակներ: | Binet, R, Lambert, J-P, Tomkova, M, Tischfield, S, Baggiolini, A, Picaud, S, Sarkar, S, Louphrasitthiphol, P, Dias, D, Carreira, S, Humphrey, TC, Fillipakopoulos, P, White, R, Goding, CR |
---|---|
Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
Cold Spring Harbor Laboratory Press
2024
|
Նմանատիպ նյութեր
-
DNA damage-induced interaction between a lineage addiction oncogenic transcription factor and the MRN complex shapes a tissue-specific DNA Damage Response and cancer predisposition
: Binet, R, և այլն
Հրապարակվել է: (2023) -
ABCB5 is activated by MITF and β‐catenin and is associated with melanoma differentiation
: Louphrasitthiphol, P, և այլն
Հրապարակվել է: (2019) -
The MITF regulatory network in melanoma
: Chauhan, JS, և այլն
Հրապարակվել է: (2022) -
MITF controls the TCA cycle to modulate the melanoma hypoxia response
: Louphrasitthiphol, P, և այլն
Հրապարակվել է: (2019) -
Acetylation reprograms MITF target selectivity and residence time
: Louphrasitthiphol, P, և այլն
Հրապարակվել է: (2023)