Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer.

Human colorectal cancer cell lines are used widely to investigate tumor biology, experimental therapy, and biomarkers. However, to what extent these established cell lines represent and maintain the genetic diversity of primary cancers is uncertain. In this study, we profiled 70 colorectal cancer ce...

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Bibliographic Details
Main Authors: Mouradov, D, Sloggett, C, Jorissen, R, Love, C, Li, S, Burgess, A, Arango, D, Strausberg, R, Buchanan, D, Wormald, S, O'Connor, L, Wilding, J, Bicknell, D, Tomlinson, I, Bodmer, W, Mariadason, J, Sieber, O
Format: Journal article
Language:English
Published: 2014