Glutamate acts as a key signal linking glucose metabolism to incretin/cAMP action to amplify insulin secretion.

Glutamate acts as a key signal linking glucose metabolism to incretin/cAMP action to amplify insulin secretion.

Incretins, hormones released by the gut after meal ingestion, are essential for maintaining systemic glucose homeostasis by stimulating insulin secretion. The effect of incretins on insulin secretion occurs only at elevated glucose concentrations and is mediated by cAMP signaling, but the mechanism ...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính:	Gheni, G, Ogura, M, Iwasaki, M, Yokoi, N, Minami, K, Nakayama, Y, Harada, K, Hastoy, B, Wu, X, Takahashi, H, Kimura, K, Matsubara, T, Hoshikawa, R, Hatano, N, Sugawara, K, Shibasaki, T, Inagaki, N, Bamba, T, Mizoguchi, A, Fukusaki, E, Rorsman, P, Seino, S
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	Elsevier 2014

Những quyển sách tương tự

Glutamate Acts as a Key Signal Linking Glucose Metabolism to Incretin/cAMP Action to Amplify Insulin Secretion
Bằng: Ghupurjan Gheni, et al.
Được phát hành: (2014-10-01)

Stimulatory effect of imeglimin on incretin secretion
Bằng: Quan Yingyue, et al.
Được phát hành: (2023-06-01)

Essential roles of aspartate aminotransferase 1 and vesicular glutamate transporters in β-cell glutamate signaling for incretin-induced insulin secretion.
Bằng: Naoya Murao, et al.
Được phát hành: (2017-01-01)

Action of incretins on the pancreatic alpha cell
Bằng: McCulloch, L, et al.
Được phát hành: (2015)

The journey to understanding incretin systems: Theory, practice and more theory
Bằng: Daisuke Yabe, et al.
Được phát hành: (2019-09-01)

Why Are Incretin-Based Therapies More Efficient in East Asians? Perspectives from the Pathophysiology of Type 2 Diabetes and East Asian Dietary Habits
Bằng: Daisuke Yabe, et al.
Được phát hành: (2015-11-01)

The integrated incretin effect is reduced by both glucose intolerance and obesity in Japanese subjects
Bằng: Akihiro Hamasaki, et al.
Được phát hành: (2024-06-01)

An analysis of intestinal morphology and incretin-producing cells using tissue optical clearing and 3-D imaging
Bằng: Tomonobu Hatoko, et al.
Được phát hành: (2022-10-01)

Tumor‐like features of gene expression and metabolic profiles in enlarged pancreatic islets are associated with impaired incretin‐induced insulin secretion in obese diabetes: A study of Zucker fatty diabetes mellitus rat
Bằng: Tomohide Hayami, et al.
Được phát hành: (2020-11-01)

Inflammation and Incretins
Bằng: Amitabh Hatwal
Được phát hành: (2012-01-01)

Cellular regulation of islet hormone secretion by the incretin hormone glucagon-like peptide 1.
Bằng: Gromada, J, et al.
Được phát hành: (1998)

The associations of incretin hormone concentration with gestational diabetes mellitus
Bằng: Tatiana V. Saprina, et al.
Được phát hành: (2016-05-01)

Incretin Mimetics in the Indian Context: Revisiting Exenatide
Bằng: Shambo S Samajdar, et al.
Được phát hành: (2022-08-01)

Pleiotropic effects of incretins
Bằng: Vishal Gupta
Được phát hành: (2012-01-01)

Recent clinical and pharmacological advancements of incretin-based therapy and the effects of incretin on physiology
Bằng: Bhaskar Pal, et al.
Được phát hành: (2024-01-01)

Does Incretin Agonism Have Sustainable Efficacy?
Bằng: Sok-Ja Janket, et al.
Được phát hành: (2024-11-01)

The Gut Microbiome’s Influence on Incretins and Impact on Blood Glucose Control
Bằng: Ajay S. Dulai, et al.
Được phát hành: (2024-11-01)

Incretin hormones as immunomodulators of atherosclerosis
Bằng: Nuria eAlonso, et al.
Được phát hành: (2012-09-01)

Understanding the Cardiovascular Effects of Incretin
Bằng: Ji Sung Yoon, et al.
Được phát hành: (2011-10-01)

Incretins in patients with rheumatoid arthritis
Bằng: Beatriz Tejera-Segura, et al.
Được phát hành: (2017-10-01)

Stimulation of incretin secreting cells
Bằng: Ramona Pais, et al.
Được phát hành: (2016-02-01)

Abnormal gut microbiota and impaired incretin effect as a cause of type 2 diabetes mellitus
Bằng: T. Y. Demidova, et al.
Được phát hành: (2022-03-01)

Achieving equitable access to incretin-based therapies in cardiovascular care
Bằng: Tina K. Reddy, et al.
Được phát hành: (2024-10-01)

Role of fasting duration and weekday in incretin and glucose regulation
Bằng: Kim K B Clemmensen, et al.
Được phát hành: (2020-04-01)

Recent advances in incretin-based therapies.
Bằng: Russell-Jones, D, et al.
Được phát hành: (2012)

Incretin Effects and Enteral Feed Transitions
Bằng: Ummu Kulthum, Jamaludin, et al.
Được phát hành: (2014)

Mechanisms of neuroprotective action of incretin mimetics
Bằng: Timur Dmitrievich Vlasov, et al.
Được phát hành: (2016-01-01)

Incretin-based therapy: renal effects
Bằng: Anton Ivanovich Korbut, et al.
Được phát hành: (2016-01-01)

Harnessing the Incretin System with Multi-Agonists
Bằng: Martin B Whyte, et al.
Được phát hành: (2022-10-01)

Editorial: Incretin agonists in the treatment of obesity
Bằng: Xiaodong Sun, et al.
Được phát hành: (2023-08-01)

Symposium 19: Secretagogues: sulfonylureas and incretins
Bằng: Víctor Commendatore
Được phát hành: (2020-11-01)

Insulin and incretin responses to grazing in insulin‐dysregulated and healthy ponies
Bằng: Danielle M. Fitzgerald, et al.
Được phát hành: (2019-01-01)

PANCREATIC AND EXTRA-PANCREATIC EFFECTS OF INCRETINS AND PERSPECTIVES FOR STUDYING ENTEROINSULIN HORMONAL SYSTEM DURING GESTATIONAL DISORDER OF CARBOHYDRATE METABOLISM
Bằng: T. V. Saprina, et al.
Được phát hành: (2013-06-01)

Incretin-based therapies: new treatments for type 2 diabetes in the new millennium
Bằng: Joan Khoo, et al.
Được phát hành: (2009-08-01)

SAVOR-TIMI to DECLARE-TIMI: A review on cardiovascular outcome trials of incretin-modulators and gliflozins
Bằng: Awadhesh K Singh, et al.
Được phát hành: (2019-01-01)

Impact of Incretin-Based Therapies on Adipokines and Adiponectin
Bằng: Habib Yaribeygi, et al.
Được phát hành: (2021-01-01)

The Impact of Incretin-Based Medications on Lipid Metabolism
Bằng: Habib Yaribeygi, et al.
Được phát hành: (2021-01-01)

Incretins today: multiple effects and therapeutic potential
Bằng: Oksana V. Tsygankova, et al.
Được phát hành: (2019-03-01)

Anti-atherosclerotic effect of incretin receptor agonists
Bằng: Xin Wang, et al.
Được phát hành: (2024-10-01)

Tirzepatide – a new analogue of incretin hormones
Bằng: Gabriela Anglart, et al.
Được phát hành: (2023-10-01)