Adenoviral-mediated delivery of a viral chemokine binding protein blocks CC-chemokine activity in vitro and in vivo.
Chemokines are important mediators of leukocyte recruitment and activation that play critical roles in the pathology of inflammatory diseases such as atherosclerosis, rheumatoid arthritis and asthma. The vaccinia virus (strain Lister) expresses a 35 kDa soluble protein ('35K') that binds a...
Main Authors: | Bursill, C, Cai, S, Channon, K, Greaves, D |
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פורמט: | Journal article |
שפה: | English |
יצא לאור: |
2003
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פריטים דומים
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Adenoviral mediated delivery of a vaccinia viral protein (35K) blocks CC-chemokine activity in vitro and in vivo and may therefore be a useful therapeutic strategy to reduce the initiation and progression of CC-chemokine induced atherosclerosis
מאת: Bursill, C, et al.
יצא לאור: (2003) -
A membrane-bound vaccinia viral protein 'mem35k' blocks CC-chemokine induced cell migration and CC-chemokine activity in vitro
מאת: Bursill, C, et al.
יצא לאור: (2005) -
Membrane-bound CC chemokine inhibitor 35K provides localized inhibition of CC chemokine activity in vitro and in vivo.
מאת: Bursill, C, et al.
יצא לאור: (2006) -
Adenoviral-mediated delivery of a CC-chemokine inhibitor ('35K') attenuates atherosclerotic plaque formation in apolipoprotein E-knockout mice
מאת: Bursill, C, et al.
יצא לאור: (2004) -
Adenoviral delivery of CC-chemokine inhibitor '35K' reduces macrophage recruitment and atherosclerosis in ApoE knockout mice
מאת: Bursill, C, et al.
יצא לאור: (2004)