Modular and automated synthesis of oligonucleotide-small molecule conjugates for cathepsin B mediated traceless release of payloads † ‡

Modular and automated synthesis of oligonucleotide-small molecule conjugates for cathepsin B mediated traceless release of payloads † ‡

The reversible attachment of small molecules to oligonucleotides provides versatile tools for the development of improved oligonucleotide therapeutics. However, cleavable linkers in the oligonucleotide field are scarce, particularly with respect to the requirement for traceless release of the payloa...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Jin, C, Li, S, Vallis, KA, El-Sagheer, AH, Brown, T
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	Royal Society of Chemistry 2024

समान संसाधन

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