Kinetics of expansion of epitope-specific T cell responses during primary HIV-1 infection.

Kinetics of expansion of epitope-specific T cell responses during primary HIV-1 infection.

Multiple lines of evidence support a role for CD8(+) T cells in control of acute/early HIV replication; however, features of the primary HIV-specific CD8(+) T cell response that may impact on the efficiency of containment of early viral replication remain poorly defined. In this study, we performed...

Full description

Bibliographic Details
Main Authors:	Turnbull, E, Wong, M, Wang, S, Wei, X, Jones, N, Conrod, K, Aldam, D, Turner, J, Pellegrino, P, Keele, B, Williams, I, Shaw, G, Borrow, P
Format:	Journal article
Language:	English
Published:	2009

Similar Items

HIV-1 epitope-specific CD8+ T cell responses strongly associated with delayed disease progression cross-recognize epitope variants efficiently.
by: Turnbull, E, et al.
Published: (2006)

Escape is a more common mechanism than avidity reduction for evasion of CD8+ T cell responses in primary human immunodeficiency virus type 1 infection.
by: Turnbull, E, et al.
Published: (2011)

Chronic HIV infection affects the expression of the 2 transcription factors required for CD8 T-cell differentiation into cytolytic effectors.
by: Ribeiro-dos-Santos, P, et al.
Published: (2012)

Escape is a more common mechanism than avidity reduction for evasion of CD8+ T cell responses in primary human immunodeficiency virus type 1 infection
by: Williams Ian, et al.
Published: (2011-06-01)

Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infection.
by: Ferrari, G, et al.
Published: (2011)

Integrating in silico and in vitro analysis of peptide binding affinity to HLA-Cw*0102: a bioinformatic approach to the prediction of new epitopes.
by: Walshe, V, et al.
Published: (2009)

Association of strong virus-specific CD4 T cell responses with efficient natural control of primary HIV-1 infection.
by: Gloster, SE, et al.
Published: (2004)

Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infection.
by: Guido Ferrari, et al.
Published: (2011-02-01)

The promise and challenge of anti-HIV cellular immunity.
by: Borrow, P, et al.
Published: (2006)

Induction of a strong HIV-specific CD8+ T cell response in mice using a fowlpox virus vector expressing an HIV-1 multi-CTL-epitope polypeptide.
by: Vázquez Blomquist, D, et al.
Published: (2002)

Population-specific evolution of HIV Gag epitopes in genetically diverged patients.
by: Abidi, S, et al.
Published: (2013)

The immune response to human immunodeficiency virus type 1 (HIV-1)
by: Turnbull, E, et al.
Published: (2005)

Major expansion of CD8+ T cells with a predominant V beta usage during the primary immune response to HIV.
by: Pantaleo, G, et al.
Published: (1994)

Broad TCR usage in functional HIV-1-specific CD8+ T cell expansions driven by vaccination during highly active antiretroviral therapy.
by: Yang, H, et al.
Published: (2007)

Expansion of epitope cross-reactivity by anti-idiotype modulation of the primary humoral response.
by: Denisova, G, et al.
Published: (2000)

Innate immune responses in primary HIV-1 infection.
by: Borrow, P, et al.
Published: (2008)

Integrating in silico and in vitro analysis of peptide binding affinity to HLA-Cw*0102: a bioinformatic approach to the prediction of new epitopes.
by: Valerie A Walshe, et al.
Published: (2009-11-01)

Analysis of the Relationship Between Founder Virus Fitness, Primary T Cell Response Breadth and Viral Control in Acute HIV-1 Infection
by: Pfafferott, K, et al.
Published: (2013)

ANALYSIS OF THE ANTIVIRAL CYTOTOXIC T-LYMPHOCYTE RESPONSE IN PRIMARY HIV-1
by: Borrow, P, et al.
Published: (1995)

Antisense-Derived HIV-1 cryptic Epitopes are not major drivers of viral evolution
by: Borrow, P, et al.
Published: (2018)

Vertical T cell immunodominance and epitope entropy determine HIV-1 escape.
by: Liu, M, et al.
Published: (2013)

In vitro expansion of Wilms’ tumor protein 1 epitope-specific primary T cells from healthy human peripheral blood mononuclear cells
by: Sanne van der Heijden, et al.
Published: (2023-03-01)

Screening for HIV-specific T-cell responses using overlapping 15-mer peptide pools or optimized epitopes.
by: Beattie, T, et al.
Published: (2004)

P04-43. Neutralizing antibody responses against conformational envelope epitopes in early HIV-1 infection
by: Hahn BH, et al.
Published: (2009-10-01)

Kinetics of HIV-1 CTL epitopes recognized by HLA I alleles in HIV-infected individuals at times near primary infection: the Provir/Latitude45 study.
by: Jennifer Papuchon, et al.
Published: (2014-01-01)

Structural dynamics reveal isolate-specific differences at neutralization epitopes on HIV Env
by: Edgar A. Hodge, et al.
Published: (2022-06-01)

Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus.
by: Borrow, P, et al.
Published: (1997)

Epitope-Specific Vaccination Limits Clonal Expansion of Heterologous Naive T Cells during Viral Challenge
by: Lexus R. Johnson, et al.
Published: (2016-10-01)

Adaptive reconfiguration of natural killer cells in HIV-1 infection
by: Peppa, D, et al.
Published: (2018)

Epitope mapping of broadly neutralizing HIV-2 human monoclonal antibodies.
by: Kong, R, et al.
Published: (2012)

The magnitude and kinetics of the mucosal HIV-specific CD8+ T lymphocyte response and virus RNA load in breast milk
by: Mahlokozera, T, et al.
Published: (2011)

The magnitude and kinetics of the mucosal HIV-specific CD8+ T lymphocyte response and virus RNA load in breast milk.
by: Mahlokozera, T, et al.
Published: (2011)

Cytomegalovirus (CMV) epitope-specific CD4(+) T cells are inflated in HIV(+) CMV(+) subjects
by: Abana, CO, et al.
Published: (2017)

EPITOPE MAPPING OF A NOVEL B27-SPECIFIC ANTIBODY
by: Giles, J, et al.
Published: (2011)

Oligoclonal expansions of CD8(+) T cells in chronic HIV infection are antigen specific.
by: Wilson, J, et al.
Published: (1998)

Rationally designed carbohydrate-occluded epitopes elicit HIV-1 Env-specific antibodies
by: Cheng Zhu, et al.
Published: (2019-02-01)

Expansion and Refinement of Deep Sequence-Coupled Biopanning Technology for Epitope-Specific Antibody Responses in Human Serum
by: Nikole L. Warner, et al.
Published: (2020-09-01)

Cellular and humoral antigenic epitopes in HIV and SIV.
by: Nixon, D, et al.
Published: (1992)

Epitopes of the CD4 antigen and HIV infection.
by: Sattentau, Q, et al.
Published: (1986)

HIV-1 protective epitope-specific CD8+ T cells in HIV-1-exposed seronegative individuals
by: Takayuki Chikata, et al.
Published: (2023-11-01)