Combining tandem mass spectrometry with ion mobility separation to determine the architecture of polydisperse proteins

Polydispersity presents a considerable challenge for the detailed molecular characterisation of many proteins. This is because in most biophysical and structural biology approaches the molecules in solution are ensemble-averaged, obscuring differences between individual proteins or conformational st...

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Bibliografske podrobnosti
Main Authors: Shepherd, D, Marty, M, Giles, K, Baldwin, A, Benesch, J
Format: Journal article
Jezik:English
Izdano: Elsevier 2015

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