Osteocyte density in aging subjects is enhanced in bone adjacent to remodeling haversian systems.

Osteocyte density in aging subjects is enhanced in bone adjacent to remodeling haversian systems.

The osteocyte is a candidate regulatory cell for bone remodeling. Previously, we demonstrated that there is a substantial (approximately 50%) loss of osteocytes from their lacunae in the cortex of the elderly femoral neck. Higher occupancy was evident in tissue exhibiting high remodeling and high po...

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Bibliografiske detaljer
Main Authors:	Power, J, Loveridge, N, Rushton, N, Parker, M, Reeve, J
Format:	Journal article
Sprog:	English
Udgivet:	2002

Lignende værker

Osteocyte density in the human femoral neck is greater in osteonal bone adjacent to remodeling compared to resting Haversian canals.
af: Power, J, et al.
Udgivet: (2000)

Osteocyte density is higher in osteonal bone surrounding remodelling vs. quiescent canals in the human femoral neck.
af: Power, J, et al.
Udgivet: (2000)

Elevated osteocyte density and lacunar occupancy are associated with remodelling in the elderly femoral neck
af: Power, J, et al.
Udgivet: (2002)

Merging of haversian canals within remodelling clusters: A cause of focal weakness in the femoral neck cortex?
af: Bell, L, et al.
Udgivet: (1999)

Fracture resistance in coxarthrosis: The role of cancellous bone mass and osteocyte lacunar density.
af: Jordan, G, et al.
Udgivet: (1999)

Oestrogen suppression increases Haversian resorption depth as well as remodelling activity in women with endometriosis
af: Bell, K, et al.
Udgivet: (1996)

Osteocyte lacunar occupancy in the femoral neck cortex: an association with cortical remodeling in hip fracture cases and controls.
af: Power, J, et al.
Udgivet: (2001)

Determinants of osteocyte differentiation: association of coxarthrosis with reduced osteocyte lacunar density as well as increased wall width and cancellous bone area in the femoral neck
af: Jordan, G, et al.
Udgivet: (2002)

A method to study eNOS expression in iliac osteocytes as a potential mechanism for regulating bone remodelling and BMU balance
af: Caballero-Alias, A, et al.
Udgivet: (2002)

Osteocytic expression of eNOS in the femoral neck cortex: A possible role in bone fragility.
af: Loveridge, N, et al.
Udgivet: (2001)

The ratio of osteocytic incorporation to bone matrix formation in femoral neck cancellous bone: an enhanced osteoblast work rate in the vicinity of hip osteoarthritis.
af: Jordan, G, et al.
Udgivet: (2003)

Is osteocyte viability in the femoral neck cortex decreased in cases of intracapsular hip fracture?
af: Power, J, et al.
Udgivet: (2000)

FEMORAL NECK OSTEOBLASTS: AN ALTERED RATE OF OSTEOCYTIC INCORPORATION: IMPLICATIONS FOR BONE FORMATION
af: Jordan, G, et al.
Udgivet: (2002)

Bone remodeling at the endocortical surface of the human femoral neck: a mechanism for regional cortical thinning in cases of hip fracture.
af: Power, J, et al.
Udgivet: (2003)

Endocortical remodeling in the human femoral neck: Increased bone resorption surfaces across the 'neutral loading axis' of hip fracture cases.
af: Power, J, et al.
Udgivet: (2002)

Intracapsular hip fractures and osteocyte lacunar occupancy.
af: Power, J, et al.
Udgivet: (1999)

Identification of apoptotic changes in osteocytes in normal and pathological human bone.
af: Noble, B, et al.
Udgivet: (1997)

Osteocytic sclerostin expression is locally reduced at the site of femoral neck fracture
af: Power, J, et al.
Udgivet: (2011)

Osteocyte recruitment declines as the osteon fills in: interacting effects of osteocytic sclerostin and previous hip fracture on the size of cortical canals in the femoral neck.
af: Power, J, et al.
Udgivet: (2012)

Osteocyte function, osteocyte death and bone fracture resistance.
af: Noble, B, et al.
Udgivet: (2000)

Automatic Detection of Cortical Bones Haversian Osteonal Boundaries
af: Ilige Hage, et al.
Udgivet: (2015-10-01)

Patterns of osteocytic endothelial nitric oxide synthase expression in the femoral neck cortex: differences between cases of intracapsular hip fracture and controls.
af: Loveridge, N, et al.
Udgivet: (2002)

Decreased bone hardness in hip fracture: Regional changes and the association with bone remodelling
af: Loveridge, N, et al.
Udgivet: (2003)

Coxarthrosis: Protection against hip fracture is associated with decreased lacunar density and increased cancellous bone mass.
af: Jordan, G, et al.
Udgivet: (2000)

Intracapsular hip fracture: increased cortical remodeling in the thinned and porous anterior region of the femoral neck.
af: Bell, K, et al.
Udgivet: (1999)

Evidence for bone formation on the external "periosteal" surface of the femoral neck: a comparison of intracapsular hip fracture cases and controls.
af: Power, J, et al.
Udgivet: (2003)

Bone mineralization density and femoral neck fragility.
af: Loveridge, N, et al.
Udgivet: (2004)

Sclerostin expression by osteocytes is a delayed event; Implications for the control of bone formation
af: Poole, K, et al.
Udgivet: (2005)

Sclerostin is a delayed secreted product of osteocytes that inhibits bone formation.
af: Poole, K, et al.
Udgivet: (2005)

Osteocytes expressing ENOs are peripherally located in cortical BMU's: A role in maintaining cortical integrity?
af: Loveridge, N, et al.
Udgivet: (2001)

Associations in bone turnover between the endocortical and cortical compartments of the human femoral neck
af: Power, J, et al.
Udgivet: (2003)

Importance of osteocyte-mediated regulation of bone remodelling in inflammatory bone disease
af: Johanna Intemann, et al.
Udgivet: (2020-02-01)

Automated human cortical bone Haversian canal histomorphometric comparison system
af: Abdullah, Hadi, et al.
Udgivet: (2020)

Mechanical properties of cortical bones related to temperature and orientation of Haversian canals
af: Zhichao Ma, et al.
Udgivet: (2020-01-01)

Spatial clustering of remodeling osteons in the femoral neck cortex: a cause of weakness in hip fracture?
af: Jordan, G, et al.
Udgivet: (2000)

Osteocyte sclerostin expression: Regulator of BMU balance in osteoarthritis and osteoporosis?
af: Loveridge, N, et al.
Udgivet: (2007)

Osteocyte function and clinical bone disease: Pathogenesis and treatment
af: Reeve, J
Udgivet: (2007)

Increased cancellous bone in the femoral neck of patients with coxarthrosis (hip osteoarthritis): a positive remodeling imbalance favoring bone formation.
af: Jordan, G, et al.
Udgivet: (2003)

Osteoclastic cortical erosion as a determinant of subperiosteal osteoblastic bone formation in the femoral neck's response to BMU imbalance. Effects of stance-related loading and hip fracture.
af: Power, J, et al.
Udgivet: (2005)

Osteocyte apoptosis and functional strain in bone
af: Noble, B, et al.
Udgivet: (1997)