Detergent-free extraction of a functional low-expressing GPCR from a human cell line

Dopamine receptors (DRs) are class A G-Protein Coupled Receptors (GPCRs) prevalent in the central nervous system (CNS). These receptors mediate physiological functions ranging from voluntary movement and reward recognition to hormonal regulation and hypertension. Drugs targeting dopaminergic neurotr...

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Bibliographic Details
Main Authors: Bada Juarez, JF, Muñoz-García, JC, Inácio Dos Reis, R, Henry, A, McMillan, D, Kriek, M, Wood, M, Vandenplas, C, Sands, Z, Castro, L, Taylor, R, Watts, A
Format: Journal article
Language:English
Published: Elsevier 2019