Influence of the combination and phase variation status of the haemoglobin receptors HmbR and HpuAB on meningococcal virulence.

Neisseria meningitidis can utilize haem, haemoglobin and haemoglobin-haptoglobin complexes as sources of iron via two TonB-dependent phase variable haemoglobin receptors, HmbR and HpuAB. HmbR is over-represented in disease isolates, suggesting a link between haemoglobin acquisition and meningococcal...

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主要な著者: Tauseef, I, Harrison, O, Wooldridge, K, Feavers, I, Neal, K, Gray, S, Kriz, P, Turner, D, Ala'Aldeen, D, Maiden, M, Bayliss, C
フォーマット: Journal article
言語:English
出版事項: 2011