Single-dose tafenoquine to prevent relapse of Plasmodium vivax malaria

<p><strong>Background</strong> Treatment of Plasmodium vivax malaria requires the clearing of asexual parasites, but relapse can be prevented only if dormant hypnozoites are cleared from the liver (a treatment termed “radical cure”). Tafenoquine is a single-dose 8-aminoquinoline th...

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Main Authors: Lacerda, MVG, Llanos-Cuentas, A, Krudsood, S, Lon, C, Saunders, DL, Mohammed, R, Yilma, D, Batista Pereira, D, Espino, FEJ, Mia, RZ, Chuquiyauri, R, Val, F, Casapía, M, Monteiro, WM, Brito, MAM, Costa, MRF, Buathong, N, Noedl, H, Diro, E, Getie, S, Wubie, KM, Abdissa, A, Zeynudin, A, Abebe, C, Tada, MS, Brand, F, Beck, H-P, Angus, B, Duparc, S, Kleim, J-P, Kellam, LM, Rousell, VM, Jones, SW, Hardaker, E, Mohamed, K, Clover, DD, Fletcher, K, Breton, JJ, Ugwuegbulam, CO, Green, JA, Koh, GCKW
Format: Journal article
Language:English
Published: Massachusetts Medical Society 2019