Neuropsychological and neuroimaging evidence for the involvement of the frontal lobes in depression: 20 years on
In 1997, neuropsychological and neuroimaging evidence supported the involvement of the frontal lobes and indeed the brain in depression. This was a challenge to conventional phenomenology and linked with the imperative to use neuroscience to understand major mental illness. Since that time, we are s...
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| Format: | Journal article |
| Language: | English |
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SAGE Publications
2016
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| _version_ | 1797088212165853184 |
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| author | Goodwin, G |
| author_facet | Goodwin, G |
| author_sort | Goodwin, G |
| collection | OXFORD |
| description | In 1997, neuropsychological and neuroimaging evidence supported the involvement of the frontal lobes and indeed the brain in depression. This was a challenge to conventional phenomenology and linked with the imperative to use neuroscience to understand major mental illness. Since that time, we are seeing ever more convincing evidence for the genetic basis of mental illness (including depression), relevant abnormality in grey and white matter and neuropsychological analysis of brain function. It has proved more difficult to pin down structural abnormality in major depression at the cellular level, but a focus on glial cells is increasingly justified by the evidence. Neuroscience continues to be a buttress against anti-scientific impulses in psychiatry and can help attract young people to enter it as a profession. |
| first_indexed | 2024-03-07T02:46:45Z |
| format | Journal article |
| id | oxford-uuid:ac4cf3e4-0470-4e62-abbd-ea3c005668cd |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T02:46:45Z |
| publishDate | 2016 |
| publisher | SAGE Publications |
| record_format | dspace |
| spelling | oxford-uuid:ac4cf3e4-0470-4e62-abbd-ea3c005668cd2022-03-27T03:28:03ZNeuropsychological and neuroimaging evidence for the involvement of the frontal lobes in depression: 20 years onJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:ac4cf3e4-0470-4e62-abbd-ea3c005668cdEnglishSymplectic Elements at OxfordSAGE Publications2016Goodwin, GIn 1997, neuropsychological and neuroimaging evidence supported the involvement of the frontal lobes and indeed the brain in depression. This was a challenge to conventional phenomenology and linked with the imperative to use neuroscience to understand major mental illness. Since that time, we are seeing ever more convincing evidence for the genetic basis of mental illness (including depression), relevant abnormality in grey and white matter and neuropsychological analysis of brain function. It has proved more difficult to pin down structural abnormality in major depression at the cellular level, but a focus on glial cells is increasingly justified by the evidence. Neuroscience continues to be a buttress against anti-scientific impulses in psychiatry and can help attract young people to enter it as a profession. |
| spellingShingle | Goodwin, G Neuropsychological and neuroimaging evidence for the involvement of the frontal lobes in depression: 20 years on |
| title | Neuropsychological and neuroimaging evidence for the involvement of the frontal lobes in depression: 20 years on |
| title_full | Neuropsychological and neuroimaging evidence for the involvement of the frontal lobes in depression: 20 years on |
| title_fullStr | Neuropsychological and neuroimaging evidence for the involvement of the frontal lobes in depression: 20 years on |
| title_full_unstemmed | Neuropsychological and neuroimaging evidence for the involvement of the frontal lobes in depression: 20 years on |
| title_short | Neuropsychological and neuroimaging evidence for the involvement of the frontal lobes in depression: 20 years on |
| title_sort | neuropsychological and neuroimaging evidence for the involvement of the frontal lobes in depression 20 years on |
| work_keys_str_mv | AT goodwing neuropsychologicalandneuroimagingevidencefortheinvolvementofthefrontallobesindepression20yearson |