A genome-wide association study identifies genetic loci associated with specific lobar brain volumes

A genome-wide association study identifies genetic loci associated with specific lobar brain volumes

Brain lobar volumes are heritable but genetic studies are limited. We performed genome-wide association studies of frontal, occipital, parietal and temporal lobe volumes in 16,016 individuals, and replicated our findings in 8,789 individuals. We identified six genetic loci associated with specific l...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	van der Lee, SJ, Knol, MJ, Chauhan, G, Satizabal, CL, Smith, AV, Hofer, E, Bis, JC, Hibar, DP, Hilal, S, van den Akker, EB, Arfanakis, K, Bernard, M, Yanek, LR, Amin, N, Crivello, F, Cheung, JW, Harris, TB, Saba, Y, Lopez, OL, Li, S, van der Grond, J, Yu, L, Paus, T, Roshchupkin, GV, Amouyel, P, Jahanshad, N, Taylor, KD, Yang, Q, Mathias, RA, Boehringer, S, Mazoyer, B, Rice, K, Cheng, CY, Maillard, P, van Heemst, D, Wong, TY, Niessen, WJ, Beiser, AS, Beekman, M, Zhao, W, Nyquist, PA, Chen, C, Launer, LJ, Psaty, BM, Ikram, MK, Vernooij, MW, Schmidt, H, Pausova, Z, Becker, DM, De Jager, PL
Formáid:	Journal article
Teanga:	English
Foilsithe / Cruthaithe:	Nature Research 2019

Míreanna comhchosúla

Diagnostic value of cerebrospinal fluid tau, neurofilament, and progranulin in definite frontotemporal lobar degeneration
de réir: Joery Goossens, et al.
Foilsithe / Cruthaithe: (2018-03-01)

Procalcitonin: in Lobar and Non-Lobar Pneumonia in Children
de réir: Farhad Heydarian, et al.
Foilsithe / Cruthaithe: (2018-07-01)

Plasma trimethylamine N-oxide (TMAO): associations with cognition, neuroimaging, and dementia
de réir: Yaqub, A, et al.
Foilsithe / Cruthaithe: (2024)

Within-Person Variation in Serum Thyrotropin Concentrations: Main Sources, Potential Underlying Biological Mechanisms, and Clinical Implications
de réir: Evie van der Spoel, et al.
Foilsithe / Cruthaithe: (2021-02-01)

Between hope and a hard place: Boys and young men negotiating gender, poverty and social worth in Ethiopia
de réir: Crivello, G, et al.
Foilsithe / Cruthaithe: (2016)

Congenital lobar emphysema
de réir: T Sarioğlu, et al.
Foilsithe / Cruthaithe: (1983-04-01)

Aerated Lobar Collapse
de réir: Laura Haddad, et al.
Foilsithe / Cruthaithe: (2023-01-01)

Congenital Lobar Emphysema
de réir: Divya Chandran-Mahaldar, et al.
Foilsithe / Cruthaithe: (2009-01-01)

Congenital lobar emphysema
de réir: Choh Suhil, et al.
Foilsithe / Cruthaithe: (2008-01-01)

Enfisema Lobar Congênito
de réir: Flávia Aparecida Pereira Prata Xavier, et al.
Foilsithe / Cruthaithe: (2010-10-01)

CONGENITAL LOBAR EMPHYSEMA
de réir: Zahid Gul, et al.
Foilsithe / Cruthaithe: (2014-01-01)

Risk Factors for Lobar and Non-Lobar Intracerebral Hemorrhage in Patients with Vascular Disease.
de réir: Philip H C Kremer, et al.
Foilsithe / Cruthaithe: (2015-01-01)

Presymptomatic and early pathological features of MAPT-associated frontotemporal lobar degeneration
de réir: Lucia AA Giannini, et al.
Foilsithe / Cruthaithe: (2023-08-01)

Frontotemporal Lobar Degeneration Case with an N-Terminal <i>TUBA4A</i> Mutation Exhibits Reduced TUBA4A Levels in the Brain and TDP-43 Pathology
de réir: Evelien Van Schoor, et al.
Foilsithe / Cruthaithe: (2022-03-01)

Postural drainage in intubated patients with acute lobar atelectasis - A pilot study
de réir: M. W. Krause, et al.
Foilsithe / Cruthaithe: (2000-08-01)

Selective involvement of the amygdala in systemic lupus erythematosus.
de réir: Bart J Emmer, et al.
Foilsithe / Cruthaithe: (2006-12-01)

Plasma trimethylamine N-oxide (TMAO): associations with cognition, neuroimaging, and dementia
de réir: Amber Yaqub, et al.
Foilsithe / Cruthaithe: (2024-05-01)

Genetics of frontotemporal lobar degeneration
de réir: Aswathy P, et al.
Foilsithe / Cruthaithe: (2010-10-01)

Genetics of Frontotemporal Lobar Degeneration
de réir: Daniela eGalimberti, et al.
Foilsithe / Cruthaithe: (2012-04-01)

Congenital lobar emphysema in an adult
de réir: Mir Sadaqat, et al.
Foilsithe / Cruthaithe: (2011-01-01)

Fetal Congenital Lobar Emphysema
de réir: Chun-Chieh Chia, et al.
Foilsithe / Cruthaithe: (2007-03-01)

Enfisema lobar congénito: Relato de caso Congenital lobar emphysema: Study of a case
de réir: Marcelo Cunha Fatureto, et al.
Foilsithe / Cruthaithe: (2008-12-01)

Association of early glycemic change with short-term mortality in lobar and non-lobar intracerebral hemorrhage
de réir: Paola Forti, et al.
Foilsithe / Cruthaithe: (2021-08-01)

Simplified Edinburgh and modified Boston criteria in relation to amyloid PET for lobar intracerebral hemorrhage
de réir: Laura Michiels, et al.
Foilsithe / Cruthaithe: (2022-01-01)

Association of liver enzymes and computed tomography markers of liver steatosis with familial longevity.
de réir: Michiel Sala, et al.
Foilsithe / Cruthaithe: (2014-01-01)

Sex-related and tissue-specific effects of tobacco smoking on brain atrophy: assessment in a large longitudinal cohort of healthy elderly
de réir: Quentin eDuriez, et al.
Foilsithe / Cruthaithe: (2014-11-01)

YKL-40 changes are not detected in post-mortem brain of patients with Alzheimer’s disease and frontotemporal lobar degeneration
de réir: Yanaika S. Hok-A-Hin, et al.
Foilsithe / Cruthaithe: (2022-07-01)

An Unusual Presentation of Congenital Lobar Emphysema
de réir: Daniel Arnaud, et al.
Foilsithe / Cruthaithe: (2017-01-01)

Surgical management of congenital lobar emphysema
de réir: R Doğan, et al.
Foilsithe / Cruthaithe: (1997-01-01)

Congenital lobar emphysema in monozygotic twins
de réir: Zeni Scott, et al.
Foilsithe / Cruthaithe: (2023-01-01)

Lobar torsion after lung transplantation
de réir: Mong-Wei Lin, et al.
Foilsithe / Cruthaithe: (2013-02-01)

Progranulin in frontotemporal lobar degeneration and neuroinflammation
de réir: Hutton Michael L, et al.
Foilsithe / Cruthaithe: (2007-02-01)

Mucoepidermoid Carcinomas Presented as Lobar Pneumonia
de réir: Tong Zhou, et al.
Foilsithe / Cruthaithe: (2018-01-01)

Underdiagnosis of frontotemporal lobar degeneration in Brazil
de réir: Valéria Santoro Bahia

Novel genetic loci associated with hippocampal volume.
de réir: Hibar, D, et al.
Foilsithe / Cruthaithe: (2017)

Microglia in frontotemporal lobar degeneration with progranulin or C9ORF72 mutations
de réir: Nobutaka Sakae, et al.
Foilsithe / Cruthaithe: (2019-09-01)

Pharmacological treatment of frontotemporal lobar degeneration: systematic review Tratamento farmacológico da degeneração lobar frontotemporal: revisão sistemática
de réir: Maria da Glória Portugal, et al.
Foilsithe / Cruthaithe: (2011-03-01)

Conducta anestésica en un lactante con enfisema lobar congénito Behavior of anesthesia in an infant with congenital lobar emphysema
de réir: Raúl de Jesús Nápoles Smith, et al.
Foilsithe / Cruthaithe: (2012-02-01)

VALIDATION OF A NOVEL CLINICAL NEUROVASCULAR COUPLING BIOMARKER
de réir: Suzanne E. van Dijk, et al.
Foilsithe / Cruthaithe: (2024-01-01)

Changes in brain activity after weight loss
de réir: A. M. vanOpstal, et al.
Foilsithe / Cruthaithe: (2019-10-01)