A genome-wide association study identifies genetic loci associated with specific lobar brain volumes

A genome-wide association study identifies genetic loci associated with specific lobar brain volumes

Brain lobar volumes are heritable but genetic studies are limited. We performed genome-wide association studies of frontal, occipital, parietal and temporal lobe volumes in 16,016 individuals, and replicated our findings in 8,789 individuals. We identified six genetic loci associated with specific l...

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Bibliografische gegevens
Hoofdauteurs: van der Lee, SJ, Knol, MJ, Chauhan, G, Satizabal, CL, Smith, AV, Hofer, E, Bis, JC, Hibar, DP, Hilal, S, van den Akker, EB, Arfanakis, K, Bernard, M, Yanek, LR, Amin, N, Crivello, F, Cheung, JW, Harris, TB, Saba, Y, Lopez, OL, Li, S, van der Grond, J, Yu, L, Paus, T, Roshchupkin, GV, Amouyel, P, Jahanshad, N, Taylor, KD, Yang, Q, Mathias, RA, Boehringer, S, Mazoyer, B, Rice, K, Cheng, CY, Maillard, P, van Heemst, D, Wong, TY, Niessen, WJ, Beiser, AS, Beekman, M, Zhao, W, Nyquist, PA, Chen, C, Launer, LJ, Psaty, BM, Ikram, MK, Vernooij, MW, Schmidt, H, Pausova, Z, Becker, DM, De Jager, PL
Formaat: Journal article
Taal:English
Gepubliceerd in: Nature Research 2019

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