A genome-wide association study identifies genetic loci associated with specific lobar brain volumes

A genome-wide association study identifies genetic loci associated with specific lobar brain volumes

Brain lobar volumes are heritable but genetic studies are limited. We performed genome-wide association studies of frontal, occipital, parietal and temporal lobe volumes in 16,016 individuals, and replicated our findings in 8,789 individuals. We identified six genetic loci associated with specific l...

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Bibliografski detalji
Glavni autori: van der Lee, SJ, Knol, MJ, Chauhan, G, Satizabal, CL, Smith, AV, Hofer, E, Bis, JC, Hibar, DP, Hilal, S, van den Akker, EB, Arfanakis, K, Bernard, M, Yanek, LR, Amin, N, Crivello, F, Cheung, JW, Harris, TB, Saba, Y, Lopez, OL, Li, S, van der Grond, J, Yu, L, Paus, T, Roshchupkin, GV, Amouyel, P, Jahanshad, N, Taylor, KD, Yang, Q, Mathias, RA, Boehringer, S, Mazoyer, B, Rice, K, Cheng, CY, Maillard, P, van Heemst, D, Wong, TY, Niessen, WJ, Beiser, AS, Beekman, M, Zhao, W, Nyquist, PA, Chen, C, Launer, LJ, Psaty, BM, Ikram, MK, Vernooij, MW, Schmidt, H, Pausova, Z, Becker, DM, De Jager, PL
Format: Journal article
Jezik:English
Izdano: Nature Research 2019

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