Reproductive factors and risk of ovarian cancer: a prospective study.

Associations between reproductive factors and risk of ovarian cancer were examined in a prospective study of 60,565 women in Norway. A total of 445 women were diagnosed as having ovarian cancer during follow-up, from 1961 through 1980. The highest risk was observed among nulliparous women, and the r...

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প্রধান লেখক: Kvåle, G, Heuch, I, Nilssen, S, Beral, V
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: 1988
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author Kvåle, G
Heuch, I
Nilssen, S
Beral, V
author_facet Kvåle, G
Heuch, I
Nilssen, S
Beral, V
author_sort Kvåle, G
collection OXFORD
description Associations between reproductive factors and risk of ovarian cancer were examined in a prospective study of 60,565 women in Norway. A total of 445 women were diagnosed as having ovarian cancer during follow-up, from 1961 through 1980. The highest risk was observed among nulliparous women, and the risk decreased significantly with increasing parity. The estimated odds ratio for women with 5 or more births compared with one birth was 0.46, after adjustment for age, urban/rural place of residence and occupational class. Neither age at first or last birth, nor age at menarche or menopause, nor marital status, showed significant associations with ovarian cancer risk after adjustment for parity. The apparent protective effect of high parity was observed for epithelial as well as non-epithelial cancers, and for the separate histological types of epithelial cancer except mucinous cystadenocarcinomas.
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spelling oxford-uuid:ac7bcd2c-fe42-4629-b29d-4ab06fdc35612022-03-27T03:29:21ZReproductive factors and risk of ovarian cancer: a prospective study.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:ac7bcd2c-fe42-4629-b29d-4ab06fdc3561EnglishSymplectic Elements at Oxford1988Kvåle, GHeuch, INilssen, SBeral, VAssociations between reproductive factors and risk of ovarian cancer were examined in a prospective study of 60,565 women in Norway. A total of 445 women were diagnosed as having ovarian cancer during follow-up, from 1961 through 1980. The highest risk was observed among nulliparous women, and the risk decreased significantly with increasing parity. The estimated odds ratio for women with 5 or more births compared with one birth was 0.46, after adjustment for age, urban/rural place of residence and occupational class. Neither age at first or last birth, nor age at menarche or menopause, nor marital status, showed significant associations with ovarian cancer risk after adjustment for parity. The apparent protective effect of high parity was observed for epithelial as well as non-epithelial cancers, and for the separate histological types of epithelial cancer except mucinous cystadenocarcinomas.
spellingShingle Kvåle, G
Heuch, I
Nilssen, S
Beral, V
Reproductive factors and risk of ovarian cancer: a prospective study.
title Reproductive factors and risk of ovarian cancer: a prospective study.
title_full Reproductive factors and risk of ovarian cancer: a prospective study.
title_fullStr Reproductive factors and risk of ovarian cancer: a prospective study.
title_full_unstemmed Reproductive factors and risk of ovarian cancer: a prospective study.
title_short Reproductive factors and risk of ovarian cancer: a prospective study.
title_sort reproductive factors and risk of ovarian cancer a prospective study
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