Environmental factors and their timing in adult-onset multiple sclerosis
Multiple sclerosis (MS) is a common, complex neurological disease. Epidemiological data implicate both genetic and environmental factors in the etiology of MS, with various factors interacting with one another. Environmental exposures might occur long before the disease becomes clinically evident, a...
| मुख्य लेखकों: | , , , |
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| स्वरूप: | Journal article |
| भाषा: | English |
| प्रकाशित: |
Macmillan Publishers Ltd.
2010
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| विषय: |
| _version_ | 1826290664203091968 |
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| author | Handel, A Giovannoni, G Ebers, G Ramagopalan, S |
| author_facet | Handel, A Giovannoni, G Ebers, G Ramagopalan, S |
| author_sort | Handel, A |
| collection | OXFORD |
| description | Multiple sclerosis (MS) is a common, complex neurological disease. Epidemiological data implicate both genetic and environmental factors in the etiology of MS, with various factors interacting with one another. Environmental exposures might occur long before the disease becomes clinically evident, as suggested by the wide range in onset age. In this Review, we examine the key time periods during which the environment might contribute to MS susceptibility, as well as the potential environmental factors involved. Understanding the nature of environmental influences in MS is highly relevant to the development of public health measures that are aimed at preventing this debilitating disease. |
| first_indexed | 2024-03-07T02:47:39Z |
| format | Journal article |
| id | oxford-uuid:ac91076a-e9b4-475d-a9a4-c25b8646afb3 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T02:47:39Z |
| publishDate | 2010 |
| publisher | Macmillan Publishers Ltd. |
| record_format | dspace |
| spelling | oxford-uuid:ac91076a-e9b4-475d-a9a4-c25b8646afb32022-03-27T03:29:54ZEnvironmental factors and their timing in adult-onset multiple sclerosisJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:ac91076a-e9b4-475d-a9a4-c25b8646afb3NeuroscienceMultiple SclerosisEnglishOxford University Research Archive - ValetMacmillan Publishers Ltd.2010Handel, AGiovannoni, GEbers, GRamagopalan, SMultiple sclerosis (MS) is a common, complex neurological disease. Epidemiological data implicate both genetic and environmental factors in the etiology of MS, with various factors interacting with one another. Environmental exposures might occur long before the disease becomes clinically evident, as suggested by the wide range in onset age. In this Review, we examine the key time periods during which the environment might contribute to MS susceptibility, as well as the potential environmental factors involved. Understanding the nature of environmental influences in MS is highly relevant to the development of public health measures that are aimed at preventing this debilitating disease. |
| spellingShingle | Neuroscience Multiple Sclerosis Handel, A Giovannoni, G Ebers, G Ramagopalan, S Environmental factors and their timing in adult-onset multiple sclerosis |
| title | Environmental factors and their timing in adult-onset multiple sclerosis |
| title_full | Environmental factors and their timing in adult-onset multiple sclerosis |
| title_fullStr | Environmental factors and their timing in adult-onset multiple sclerosis |
| title_full_unstemmed | Environmental factors and their timing in adult-onset multiple sclerosis |
| title_short | Environmental factors and their timing in adult-onset multiple sclerosis |
| title_sort | environmental factors and their timing in adult onset multiple sclerosis |
| topic | Neuroscience Multiple Sclerosis |
| work_keys_str_mv | AT handela environmentalfactorsandtheirtiminginadultonsetmultiplesclerosis AT giovannonig environmentalfactorsandtheirtiminginadultonsetmultiplesclerosis AT ebersg environmentalfactorsandtheirtiminginadultonsetmultiplesclerosis AT ramagopalans environmentalfactorsandtheirtiminginadultonsetmultiplesclerosis |