Amplification of DNA damage by a γH2AX-targeted radiopharmaceutical.
(111)In-DTPA-anti-γH2AX-Tat, which combines an anti-γH2AX antibody with a cell-penetrating peptide, Tat, and the Auger electron-emitting radioisotope, (111)In, targets the DNA damage signalling protein, γH2AX, and has potential as a probe for imaging DNA damage in vivo. The goal of this study was to...
Κύριοι συγγραφείς: | Cornelissen, B, Darbar, S, Kersemans, V, Allen, D, Falzone, N, Barbeau, J, Smart, S, Vallis, K |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
Elsevier
2012
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Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
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PET imaging of DNA damage using (89)Zr-labelled anti-γH2AX-TAT immunoconjugates.
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Molecular radiotherapy using cleavable radioimmunoconjugates that target eGFR and γH2AX
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