Amplification of DNA damage by a γH2AX-targeted radiopharmaceutical.

Amplification of DNA damage by a γH2AX-targeted radiopharmaceutical.

Taispeáin leaganacha eile (1)

(111)In-DTPA-anti-γH2AX-Tat, which combines an anti-γH2AX antibody with a cell-penetrating peptide, Tat, and the Auger electron-emitting radioisotope, (111)In, targets the DNA damage signalling protein, γH2AX, and has potential as a probe for imaging DNA damage in vivo. The goal of this study was to...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	Cornelissen, B, Darbar, S, Kersemans, V, Allen, D, Falzone, N, Barbeau, J, Smart, S, Vallis, K
Formáid:	Journal article
Teanga:	English
Foilsithe / Cruthaithe:	Elsevier 2012

Míreanna comhchosúla

Amplification of DNA damage by a γH2AX-targeted radiopharmaceutical
de réir: Cornelissen, B, et al.
Foilsithe / Cruthaithe: (2012)

Imaging DNA damage in vivo using gammaH2AX-targeted immunoconjugates.
de réir: Cornelissen, B, et al.
Foilsithe / Cruthaithe: (2011)

PET imaging of DNA damage using 89Zr-labelled anti-γH2AX-TAT immunoconjugates
de réir: Knight, J, et al.
Foilsithe / Cruthaithe: (2015)

PET imaging of DNA damage using (89)Zr-labelled anti-γH2AX-TAT immunoconjugates.
de réir: Knight, J, et al.
Foilsithe / Cruthaithe: (2015)

Molecular radiotherapy using cleavable radioimmunoconjugates that target eGFR and γH2AX
de réir: Cornelissen, B, et al.
Foilsithe / Cruthaithe: (2013)

Molecular radiotherapy using cleavable radioimmunoconjugates that target EGFR and γH2AX.
de réir: Cornelissen, B, et al.
Foilsithe / Cruthaithe: (2013)

Can γH2AX be used to personalise cancer treatment?
de réir: Shah, K, et al.
Foilsithe / Cruthaithe: (2013)

Advances in anticancer radiopharmaceuticals.
de réir: Jackson, MR, et al.
Foilsithe / Cruthaithe: (2013)

Imaging DNA damage response (DDR) during oncogenesis
de réir: Cornelissen, B, et al.
Foilsithe / Cruthaithe: (2013)

DNA Damage Sensor γ-H2AX Is Increased in Preneoplastic Lesions of Hepatocellular Carcinoma
de réir: Yasunobu Matsuda, et al.
Foilsithe / Cruthaithe: (2013-01-01)

Considerations for the Use of the DNA Damage Marker γ‐H2AX in Disease Modeling, Detection, Diagnosis, and Prognosis
de réir: Holly Hosking, et al.
Foilsithe / Cruthaithe: (2024-09-01)

89Zr-anti-γH2AX-TAT but not 18F-FDG allows early monitoring of response to chemotherapy in a mouse model of pancreatic ductal adenocarcinoma
de réir: Knight, J, et al.
Foilsithe / Cruthaithe: (2017)

Residual γH2AX foci as an indication of lethal DNA lesions
de réir: Banuelos C Adriana, et al.
Foilsithe / Cruthaithe: (2010-01-01)

Characterising In-111-anti-gamma H2AX-TAT in targeting the DNA damage signal associated with Wnt activated colorectal cancer
de réir: Konstantinou, M, et al.
Foilsithe / Cruthaithe: (2016)

γH2AX expression in cytological specimens as a biomarker of response to radiotherapy in solid malignancies
de réir: Shah, K, et al.
Foilsithe / Cruthaithe: (2015)

Diffusion of activated ATM explains γH2AX and MDC1 spread beyond the DNA damage site
de réir: Georgi Danovski, et al.
Foilsithe / Cruthaithe: (2024-09-01)

Arabidopsis γ-H2A.X-INTERACTING PROTEIN participates in DNA damage response and safeguards chromatin stability
de réir: Tianyi Fan, et al.
Foilsithe / Cruthaithe: (2022-12-01)

Imaging DNA damage repair in vivo following 177Lu-DOTATATE therapy
de réir: O'Neill, E, et al.
Foilsithe / Cruthaithe: (2019)

EP-2324: Non-invasive PET imaging of radiosensitive tumour regions using γH2AX-targeted immunoconjugate
de réir: Yaromina, A, et al.
Foilsithe / Cruthaithe: (2018)

DNA damage signalling histone H2AX is required for tumour growth
de réir: Lizbeth Contreras, et al.
Foilsithe / Cruthaithe: (2024-02-01)

ErbB-2 blockade and prenyltransferase inhibition alter epidermal growth factor and epidermal growth factor receptor trafficking and enhance (111)In-DTPA-hEGF Auger electron radiation therapy.
de réir: Cornelissen, B, et al.
Foilsithe / Cruthaithe: (2011)

Imaging DNA damage allows detection of preneoplasia in the BALB-neuT model of breast cancer.
de réir: Cornelissen, B, et al.
Foilsithe / Cruthaithe: (2014)

DNA Damage by Radiopharmaceuticals and Mechanisms of Cellular Repair
de réir: Yousef Khazaei Monfared, et al.
Foilsithe / Cruthaithe: (2023-12-01)

Radiation exposure lymphocyte damage assessed by γ-H2AX level using flow cytometry
de réir: Zhuoqing Chen, et al.
Foilsithe / Cruthaithe: (2024-02-01)

The Phosphorylated Form of the Histone H2AX (γH2AX) in the Brain from Embryonic Life to Old Age
de réir: Adalberto Merighi, et al.
Foilsithe / Cruthaithe: (2021-11-01)

Positioning of nucleosomes containing γ-H2AX precedes active DNA demethylation and transcription initiation
de réir: Stephanie Dobersch, et al.
Foilsithe / Cruthaithe: (2021-02-01)

Cohesin protects genes against γH2AX Induced by DNA double-strand breaks.
de réir: Pierre Caron, et al.
Foilsithe / Cruthaithe: (2012-01-01)

111In-BnDTPA-F3: an Auger electron-emitting radiotherapeutic agent that targets nucleolin.
de réir: Cornelissen, B, et al.
Foilsithe / Cruthaithe: (2012)

111In-BnDTPA-F3: An Auger electron-emitting radiotherapeutic agent that targets nucleolin
de réir: Cornelissen, B, et al.
Foilsithe / Cruthaithe: (2012)

111In-BnDTPA-F3: An Auger electron-emitting radiotherapeutic agent that targets nucleolin
de réir: Cornelissen, B, et al.
Foilsithe / Cruthaithe: (2012)

H2AX Phosphorylation: Its Role in DNA Damage Response and Cancer Therapy
de réir: Monika Podhorecka, et al.
Foilsithe / Cruthaithe: (2010-01-01)

Early detection of pancreatic cancer in KPC mice by imaging DNA damage signalling
de réir: Knight, J, et al.
Foilsithe / Cruthaithe: (2018)

Generation of an alpaca‐derived nanobody recognizing γ‐H2AX
de réir: Malini Rajan, et al.
Foilsithe / Cruthaithe: (2015-01-01)

Predictive effect of γH2AX expression on the radiosensitivity of glioma
de réir: Jun-wei WANG, et al.
Foilsithe / Cruthaithe: (2014-03-01)

In vivo Analysis of H2AX Phosphorylation Induced by γ-Radiation
de réir: Seyed Mostafa Mir, et al.
Foilsithe / Cruthaithe: (2017-03-01)

Are platinum agents, paclitaxel and irinotecan effective for clear cell carcinoma of the ovary? DNA damage detected with γH2AX induced by anticancer agents
de réir: Takatori Eriko, et al.
Foilsithe / Cruthaithe: (2012-06-01)

Osmotic Stress Interferes with DNA Damage Response and H2AX Phosphorylation in Human Keratinocytes
de réir: Laura Hoen, et al.
Foilsithe / Cruthaithe: (2022-03-01)

The role of Box A of HMGB1 in producing γH2AX associated DNA breaks in lung cancer
de réir: Sirapat Settayanon, et al.
Foilsithe / Cruthaithe: (2025-01-01)

89Zr-anti-γH2AX-TAT allows early monitoring of response to gemcitabine and capecitabine therapy in pancreatic ductal adenocarcinoma
de réir: Knight, J, et al.
Foilsithe / Cruthaithe: (2016)

Amelioration of cyclophosphamide-induced DNA damage, oxidative stress, and hepato- and neurotoxicity by Piper longum extract in rats: The role of γH2AX and 8-OHdG
de réir: Vaishali Yadav, et al.
Foilsithe / Cruthaithe: (2023-03-01)