Amplification of DNA damage by a γH2AX-targeted radiopharmaceutical.

Amplification of DNA damage by a γH2AX-targeted radiopharmaceutical.

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(111)In-DTPA-anti-γH2AX-Tat, which combines an anti-γH2AX antibody with a cell-penetrating peptide, Tat, and the Auger electron-emitting radioisotope, (111)In, targets the DNA damage signalling protein, γH2AX, and has potential as a probe for imaging DNA damage in vivo. The goal of this study was to...

书目详细资料
Main Authors:	Cornelissen, B, Darbar, S, Kersemans, V, Allen, D, Falzone, N, Barbeau, J, Smart, S, Vallis, K
格式:	Journal article
语言:	English
出版:	Elsevier 2012

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