In vivo characterization of regulatory polymorphisms by allele-specific quantification of RNA polymerase loading.

In vivo characterization of regulatory polymorphisms by allele-specific quantification of RNA polymerase loading.

In vivo characterization of regulatory polymorphisms is a key requirement for next-generation human genetic analysis. Here we describe haploChIP, a method that uses chromatin immunoprecipitation (ChIP) and mass spectrometry to identify differential protein-DNA binding in vivo associated with allelic...

Полное описание

Библиографические подробности
Главные авторы:	Knight, J, Keating, B, Rockett, K, Kwiatkowski, D
Формат:	Journal article
Язык:	English
Опубликовано:	2003

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