In vivo characterization of regulatory polymorphisms by allele-specific quantification of RNA polymerase loading.
In vivo characterization of regulatory polymorphisms is a key requirement for next-generation human genetic analysis. Here we describe haploChIP, a method that uses chromatin immunoprecipitation (ChIP) and mass spectrometry to identify differential protein-DNA binding in vivo associated with allelic...
Main Authors: | Knight, J, Keating, B, Rockett, K, Kwiatkowski, D |
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格式: | Journal article |
语言: | English |
出版: |
2003
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