Initial DNA interactions of the binuclear threading intercalator Λ,Λ-[μ-bidppz(bipy)4Ru2]4+: an NMR study with [d(CGCGAATTCGCG)]2.
Binuclear polypyridine ruthenium compounds have been shown to slowly intercalate into DNA, following a fast initial binding on the DNA surface. For these compounds, intercalation requires threading of a bulky substituent, containing one Ru(II), through the DNA base-pair stack, and the accompanying D...
Autori principali: | Wu, L, Reymer, A, Persson, C, Kazimierczuk, K, Brown, T, Lincoln, P, Nordén, B, Billeter, M |
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Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
2013
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