Reduction of cPLA2alpha overexpression: an efficient anti-inflammatory therapy for collagen-induced arthritis.

Reduction of cPLA2alpha overexpression: an efficient anti-inflammatory therapy for collagen-induced arthritis.

Cytosolic phospholipase A2alpha (cPLA2) plays an important role in the development of several inflammatory diseases. The aim of the present study is to determine whether inhibition of cPLA2 expression, using specific antisense oligonucleotides against cPLA2 (antisense), is efficient in reducing infl...

書誌詳細
主要な著者:	Raichel, L, Berger, S, Hadad, N, Kachko, L, Karter, M, Szaingurten-Solodkin, I, Williams, R, Feldmann, M, Levy, R
フォーマット:	Journal article
言語:	English
出版事項:	2008

類似資料

Modulation of the activity of cytosolic phospholipase A2α (cPLA2α) by cellular sphingolipids and inhibition of cPLA2α by sphingomyelin[S]
著者:: Hiroyuki Nakamura, 等
出版事項: (2010-04-01)

Brain lipid metabolism in the cPLA2 knockout mouse
著者:: Thad A. Rosenberger, 等
出版事項: (2003-01-01)

Effect of zinc oxide suspension on the overall filler content of the PLA/ZnO composites and cPLA/ZnO composites
著者:: Tan Mei Ai, 等
出版事項: (2023-06-01)

Long-Term Lithium Treatment Increases cPLA2 and iPLA2 Activity in Cultured Cortical and Hippocampal Neurons
著者:: Vanessa de Jesus De-Paula, 等
出版事項: (2015-11-01)

Mechanical Activation of cPLA2 Impedes Fatty Acid β‐Oxidation in Vein Grafts
著者:: Linwei Fan, 等
出版事項: (2025-01-01)

cPLA<sub>2</sub>α Enzyme Inhibition Attenuates Inflammation and Keratinocyte Proliferation
著者:: Felicity J. Ashcroft, 等
出版事項: (2020-10-01)

Cytosolic Phospholipase A2(cPLA2) Immunoreactivity Is Elevated in Alzheimer's Disease Brain
著者:: Diane T. Stephenson, 等
出版事項: (1996-02-01)

Interleukin 15 primes natural killer cells to kill via NKG2D and cPLA2 and this pathway is active in psoriatic arthritis.
著者:: Fangming Tang, 等
出版事項: (2013-01-01)

Evaluation of TNF-alpha and IL-1 blockade in collagen-induced arthritis and comparison with combined anti-TNF-alpha/anti-CD4 therapy.
著者:: Williams, R, 等
出版事項: (2000)

Highly Potent 2‑Oxoester Inhibitors of Cytosolic Phospholipase A2 (GIVA cPLA2)
著者:: Anastasia Psarra, 等
出版事項: (2018-08-01)

A distal enhancer controls cytokine-dependent human cPLA2α gene expression[S]
著者:: Justin S. Bickford, 等
出版事項: (2013-07-01)

Specific monocyte adhesion to endothelial cells induced by oxidized phospholipids involves activation of cPLA2 and lipoxygenase
著者:: Joakim Huber, 等
出版事項: (2006-05-01)

Correction to “Highly Potent 2‑Oxoester Inhibitors of Cytosolic Phospholipase A2 (GIVA cPLA2)”
著者:: Anastasia Psarra, 等
出版事項: (2019-06-01)

Involvement of the γ Isoform of cPLA<sub>2</sub> in the Biosynthesis of Bioactive <i>N-</i>Acylethanolamines
著者:: Yiman Guo, 等
出版事項: (2021-08-01)

Inhibition of sPLA₂-IIA prevents LPS-induced neuroinflammation by suppressing ERK1/2-cPLA₂α pathway in mice cerebral cortex.
著者:: Yanxiao Xiang, 等
出版事項: (2013-01-01)

Suppression of TNF-alpha expression, inhibition of Th1 activity, and amelioration of collagen-induced arthritis by rolipram.
著者:: Ross, SE, 等
出版事項: (1997)

Therapeutic actions of cyclosporine and anti-tumor necrosis factor alpha in collagen-induced arthritis and the effect of combination therapy.
著者:: Williams, R, 等
出版事項: (1998)

Structure Activity Relationship and Molecular Docking of Some Quinazolines Bearing Sulfamerazine Moiety as New 3CLpro, cPLA2, sPLA2 Inhibitors
著者:: Mohammed Abdalla Hussein, 等
出版事項: (2023-08-01)

Elamipretide alleviates pyroptosis in traumatically injured spinal cord by inhibiting cPLA2-induced lysosomal membrane permeabilization
著者:: Haojie Zhang, 等
出版事項: (2023-01-01)

The effects of myelin on macrophage activation are phenotypic specific via cPLA2 in the context of spinal cord injury inflammation
著者:: Timothy J. Kopper, 等
出版事項: (2021-03-01)

Inhibition of Cytosolic Phospholipase A2α (cPLA2α) by Medicinal Plants in Relation to Their Phenolic Content
著者:: Eva Arnold, 等
出版事項: (2015-08-01)

Formyl Peptide Receptor 2-Dependent cPLA2 and 5-LOX Activation Requires a Functional NADPH Oxidase
著者:: Tiziana Pecchillo Cimmino, 等
出版事項: (2024-02-01)

Thrombin induces ferroptosis in triple-negative breast cancer through the cPLA2α/ACSL4 signaling pathway
著者:: Shuo Xu, 等
出版事項: (2024-01-01)

cPLA2 phosphorylation at serine-515 and serine-505 is required for arachidonic acid release in vascular smooth muscle cells
著者:: Zoran Pavicevic, 等
出版事項: (2008-04-01)

TNF-alpha-induced cPLA2 expression via NADPH oxidase/reactive oxygen species-dependent NF-kappaB cascade on human pulmonary alveolar epithelial cells
著者:: Chih-Chung Lin, 等
出版事項: (2016-11-01)

Increased Expression and Activity of Brain Cortical cPLA2 Due to Chronic Lipopolysaccharide Administration in Mouse Model of Familial Alzheimer’s Disease
著者:: Mikko Gynther, 等
出版事項: (2022-11-01)

Blue light alters cellular lipidome—Light-induced lipidomic changes can be modulated by optogenetically engineered cPLA2α
著者:: Chi Zhang, 等
出版事項: (2022-12-01)

Soluble oligomers of amyloid-β peptide induce neuronal apoptosis by activating a cPLA2-dependent sphingomyelinase-ceramide pathway
著者:: Catherine Malaplate-Armand, 等
出版事項: (2006-07-01)

Collagen-induced arthritis in mice: a major role for tumor necrosis factor-alpha.
著者:: Williams, R
出版事項: (2007)

Coptisine ameliorates colitis in mice by modulating cPLA2/TRPM8/CGRP-1 signaling pathways and strengthening intestinal barrier function
著者:: Wenbin Wu, 等
出版事項: (2025-03-01)

Alveolar macrophage-derived gVPLA2 promotes ventilator-induced lung injury via the cPLA2/PGE2 pathway
著者:: Hanghang Han, 等
出版事項: (2023-12-01)

Effect of Kaempferol on Cyclooxygenase 2 (Cox2) and Cytosolic Phospholipase A2 (cPLA2) Protein Expression in BALB/c Mice
著者:: Da Rae Kang, 等
出版事項: (2018-10-01)

Gigantol ameliorates CCl4-induced liver injury via preventing activation of JNK/cPLA2/12-LOX inflammatory pathway
著者:: Yaru Xue, 等
出版事項: (2020-12-01)

Suppression of collagen-induced arthritis by continuous administration of IL-4.
著者:: Horsfall, A, 等
出版事項: (1997)

Macrophage-specific overexpression of group IIa sPLA2 increases atherosclerosis and enhances collagen deposition
著者:: Stijn A.I. Ghesquiere, 等
出版事項: (2005-02-01)

Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis.
著者:: Williams, R, 等
出版事項: (1992)

Dynamics of proinflammatory cytokine expression in the joints of mice with collagen-induced arthritis (CIA).
著者:: Marinova-Mutafchieva, L, 等
出版事項: (1997)

Targeting TNF alpha for the therapy of rheumatoid arthritis.
著者:: Maini, R, 等
出版事項: (1994)

Elucidating the role of S100A10 in CD8+ T cell exhaustion and HCC immune escape via the cPLA2 and 5-LOX axis
著者:: Ganggang Wang, 等
出版事項: (2024-08-01)

Sulforaphane attenuates platelet granule secretion through down-regulating glycoprotein VI-mediated p38 MAPK/cPLA2 signaling pathway
著者:: Xinhui Huang, 等
出版事項: (2023-12-01)