The circadian clock components BMAL1 and REV-ERBα regulate flavivirus replication

The circadian clock components BMAL1 and REV-ERBα regulate flavivirus replication

The circadian clock regulates immune responses to microbes and affects pathogen replication, but the underlying molecular mechanisms are not well understood. Here we demonstrate that the circadian components BMAL1 and REV-ERBα influence several steps in the hepatitis C virus (HCV) life cycle, includ...

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Main Authors: Zhuang, X, Magri, A, Hill, M, Lai, A, Kumar, A, Rambhatla, S, Donald, C, Lopez-Clavijo, A, Rudge, S, Pinnick, K, Chang, W, Wing, P, Brown, R, Qin, X, Simmonds, P, Baumert, T, Ray, D, Loudon, A, Balfe, P, Wakelam, M, Butterworth, S, Kohl, A, Jopling, C, Zitzmann, N, McKeating, J
格式: Journal article
出版: Springer Nature 2019

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