The p53 cofactor Strap exhibits an unexpected TPR motif and oligonucleotide-binding (OB)-fold structure.

The p53 cofactor Strap exhibits an unexpected TPR motif and oligonucleotide-binding (OB)-fold structure.

Activation of p53 target genes for tumor suppression depends on the stress-specific regulation of transcriptional coactivator complexes. Strap (stress-responsive activator of p300) is activated upon DNA damage by ataxia telangiectasia mutated (ATM) and Chk2 kinases and is a key regulator of the p53...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak:	Adams, C, Pike, A, Maniam, S, Sharpe, T, Coutts, A, Knapp, S, La Thangue, N, Bullock, A
Formatua:	Journal article
Hizkuntza:	English
Argitaratua:	2012

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