Mitochondrial damage contributes to Pseudomonas aeruginosa activation of the inflammasome and is downregulated by autophagy.

The nucleotide-binding domain, leucine-rich repeat containing family caspase recruitment domain containing 4 (NLRC4) inflammasome can be activated by pathogenic bacteria via products translocated through the microbial type III secretion apparatus (T3SS). Recent work has shown that activation of the...

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Dades bibliogràfiques
Autors principals: Jabir, MS, Hopkins, L, Ritchie, N, Ullah, I, Bayes, H, Li, D, Tourlomousis, P, Lupton, A, Puleston, D, Simon, A, Bryant, C, Evans, T
Format: Journal article
Idioma:English
Publicat: 2015

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