Stem-loop 1 of the U1 snRNP plays a critical role in the suppression of HIV-1 polyadenylation.

The inactivity or occlusion of the HIV-1 poly(A) signal when in the 5' long terminal repeat (LTR) has been mechanistically investigated. First we show that neither the homologous HIV-1 promoter nor the close proximity of this RNA processing signal to the transcript initiation site is required f...

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Bibliografiset tiedot
Päätekijät: Ashe, M, Furger, A, Proudfoot, N
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: 2000

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