Escaping high viral load exhaustion: CD8 cells with altered tetramer binding in chronic hepatitis B virus infection.

Escaping high viral load exhaustion: CD8 cells with altered tetramer binding in chronic hepatitis B virus infection.

Deletion, anergy, and a spectrum of functional impairments can affect virus-specific CD8 cells in chronic viral infections. Here we characterize a low frequency population of CD8 cells present in chronic hepatitis B virus (HBV) infection which survive in the face of a high quantity of viral antigen....

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Bibliografiske detaljer
Main Authors:	Reignat, S, Webster, G, Brown, D, Ogg, G, King, A, Seneviratne, S, Dusheiko, G, Williams, R, Maini, M, Bertoletti, A
Format:	Journal article
Sprog:	English
Udgivet:	2002

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