RNA polymerase: structural determinant of the chromatin loop and the chromosome.
Current models for RNA synthesis involve an RNA polymerase that tracks along a static template. However, research on chromatin loops suggests that the template slides past a stationary polymerase; individual polymerases tie the chromatin fibre into loops and clusters of polymerases determine the bas...
| Main Author: | |
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| Format: | Journal article |
| Language: | English |
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1994
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| _version_ | 1826290794827350016 |
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| author | Cook, P |
| author_facet | Cook, P |
| author_sort | Cook, P |
| collection | OXFORD |
| description | Current models for RNA synthesis involve an RNA polymerase that tracks along a static template. However, research on chromatin loops suggests that the template slides past a stationary polymerase; individual polymerases tie the chromatin fibre into loops and clusters of polymerases determine the basic structure of the interphase and metaphase chromosome. RNA polymerase is then both a player and a manager of the chromosome loop. |
| first_indexed | 2024-03-07T02:49:40Z |
| format | Journal article |
| id | oxford-uuid:ad3bc794-ec8d-42b1-bb0d-623c19994bd8 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T02:49:40Z |
| publishDate | 1994 |
| record_format | dspace |
| spelling | oxford-uuid:ad3bc794-ec8d-42b1-bb0d-623c19994bd82022-03-27T03:34:13ZRNA polymerase: structural determinant of the chromatin loop and the chromosome.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:ad3bc794-ec8d-42b1-bb0d-623c19994bd8EnglishSymplectic Elements at Oxford1994Cook, PCurrent models for RNA synthesis involve an RNA polymerase that tracks along a static template. However, research on chromatin loops suggests that the template slides past a stationary polymerase; individual polymerases tie the chromatin fibre into loops and clusters of polymerases determine the basic structure of the interphase and metaphase chromosome. RNA polymerase is then both a player and a manager of the chromosome loop. |
| spellingShingle | Cook, P RNA polymerase: structural determinant of the chromatin loop and the chromosome. |
| title | RNA polymerase: structural determinant of the chromatin loop and the chromosome. |
| title_full | RNA polymerase: structural determinant of the chromatin loop and the chromosome. |
| title_fullStr | RNA polymerase: structural determinant of the chromatin loop and the chromosome. |
| title_full_unstemmed | RNA polymerase: structural determinant of the chromatin loop and the chromosome. |
| title_short | RNA polymerase: structural determinant of the chromatin loop and the chromosome. |
| title_sort | rna polymerase structural determinant of the chromatin loop and the chromosome |
| work_keys_str_mv | AT cookp rnapolymerasestructuraldeterminantofthechromatinloopandthechromosome |