Cell-permeable lanthanide-platinum(IV) anti-cancer prodrugs

Platinum compounds are a vital part of our anti-cancer arsenal, and determining the location and speciation of platinum compounds is crucial. We have synthesised a lanthanide complex bearing a salicylic group (Ln = Gd, Eu) which demonstrates excellent cellular accumulation and minimal cytotoxicity....

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Detalles Bibliográficos
Autores principales: Yao, K, Karunanithy, G, Howarth, A, Holdship, P, Thompson, AL, Christensen, KE, Baldwin, AJ, Faulkner, S, Farrer, NJ
Formato: Journal article
Lenguaje:English
Publicado: Royal Society of Chemistry 2021