CDP840: a novel inhibitor of PDE-4.

CDP840: a novel inhibitor of PDE-4.

We present the in vitro characterization of a novel phosphodiesterase type 4 inhibitor, CDP840 (R-[+]-4-[2-¿3-cyclopentyloxy-4-methoxyphenyl¿-2-phenylethyl]pyridine), which has shown efficacy in a phase II allergen challenge study in asthmatics without adverse effects. CDP840 potently inhibits PDE-4...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Perry, M, O'Connell, J, Walker, C, Crabbe, T, Baldock, D, Russell, A, Lumb, S, Huang, Z, Howat, D, Allen, R, Merriman, M, Walls, J, Daniel, T, Hughes, B, Laliberte, F, Higgs, G, Owens, R
التنسيق: Journal article
اللغة:English
منشور في: 1998

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