Quinolone-3-diarylethers: a new class of antimalarial drug.

Quinolone-3-diarylethers: a new class of antimalarial drug.

The goal for developing new antimalarial drugs is to find a molecule that can target multiple stages of the parasite's life cycle, thus impacting prevention, treatment, and transmission of the disease. The 4(1H)-quinolone-3-diarylethers are selective potent inhibitors of the parasite's mit...

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Hlavní autoři: Nilsen, A, LaCrue, A, White, K, Forquer, I, Cross, R, Marfurt, J, Mather, M, Delves, M, Shackleford, D, Saenz, F, Morrisey, J, Steuten, J, Mutka, T, Li, Y, Wirjanata, G, Ryan, E, Duffy, S, Kelly, J, Sebayang, B, Zeeman, A, Noviyanti, R, Sinden, R, Kocken, C, Price, R, Avery, V, Angulo-Barturen, I, Jiménez-Díaz, M, Ferrer, S, Herreros, E, Sanz, L, Gamo, F, Bathurst, I, Burrows, J, Siegl, P, Guy, R, Winter, R, Vaidya, AB, Charman, SA, Kyle, D, Manetsch, R, Riscoe, M
Médium: Journal article
Jazyk:English
Vydáno: American Association for the Advancement of Science 2013

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