Reverse immunodynamics: a new method for identifying targets of protective immunity

Despite a dramatic increase in our ability to catalogue variation among pathogen genomes, we have made far fewer advances in using this information to identify targets of protective immunity. Epidemiological models predict that strong immune selection can cause antigenic variants to structure into g...

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Main Authors: Spensley, K, Wikramaratna, P, Penman, B, Walker, A, Smith, A, Pybus, O, Jean, L, Gupta, S, Lourenco, J
Format: Journal article
Izdano: Springer Nature 2019