Reverse immunodynamics: a new method for identifying targets of protective immunity

Reverse immunodynamics: a new method for identifying targets of protective immunity

Despite a dramatic increase in our ability to catalogue variation among pathogen genomes, we have made far fewer advances in using this information to identify targets of protective immunity. Epidemiological models predict that strong immune selection can cause antigenic variants to structure into g...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Spensley, K, Wikramaratna, P, Penman, B, Walker, A, Smith, A, Pybus, O, Jean, L, Gupta, S, Lourenco, J
Формат:	Journal article
Хэвлэсэн:	Springer Nature 2019

Ижил төстэй зүйлс

From immune equilibrium to immunodynamics
-н: Xiaoping Chen, зэрэг
Хэвлэсэн: (2022-11-01)

Immunodynamics of explanted human tumors for immuno‐oncology
-н: Agathe Dubuisson, зэрэг
Хэвлэсэн: (2020-12-01)

Radiation immunodynamics in patients with glioblastoma receiving chemoradiation
-н: Lindsey Sloan, зэрэг
Хэвлэсэн: (2024-09-01)

Endothelin B Receptor Immunodynamics in Pulmonary Arterial Hypertension
-н: Christoph Tabeling, зэрэг
Хэвлэсэн: (2022-06-01)

Immunostimulatory/Immunodynamic model of mRNA‐1273 to guide pediatric vaccine dose selection
-н: Vijay Ivaturi, зэрэг
Хэвлэсэн: (2025-01-01)

A first-in-class, non-invasive, immunodynamic biomarker approach for precision immuno-oncology
-н: Jenny Sprooten, зэрэг
Хэвлэсэн: (2022-12-01)

Loss of CD47 alters CD8+ T cell activation in vitro and immunodynamics in mice
-н: Pulak R. Nath, зэрэг
Хэвлэсэн: (2022-12-01)

Effects of neutralizing antibodies on escape from CD8+ T-cell responses in HIV-1 infection.
-н: Wikramaratna, P, зэрэг
Хэвлэсэн: (2015)

Contact between bird species of different lifespans can promote the emergence of highly pathogenic avian influenza strains.
-н: Wikramaratna, P, зэрэг
Хэвлэсэн: (2014)

Comprehensive analyses of immunodynamics and immunoreactivity in response to treatment in ALK-positive non-small-cell lung cancer
-н: Sung Sook Lee, зэрэг
Хэвлэсэн: (2020-10-01)

Mathematical Modeling Finds Disparate Interferon Production Rates Drive Strain-Specific Immunodynamics during Deadly Influenza Infection
-н: Emily E. Ackerman, зэрэг
Хэвлэсэн: (2022-04-01)

Protocol to study immunodynamics in the tumor microenvironment using a tyramide signal amplification-based immunofluorescent multiplex panel
-н: Jane Siu-Fan Li, зэрэг
Хэвлэсэн: (2024-03-01)

The interplay between environmental factors, vector competence and vaccine immunodynamics as possible explanation of the 2019 yellow fever re-emergence in Nigeria
-н: I.N. Abdullahi, зэрэг
Хэвлэсэн: (2021-05-01)

Predicting IFN-γ responses after BCG vaccination in humans from macaques: A proof-of-concept study of Immunostimulation/Immunodynamic modelling methods
-н: Rhodes, S, зэрэг
Хэвлэсэн: (2017)

MANTIS: An R package that simulates multilocus models of pathogen evolution
-н: Lourenço, J, зэрэг
Хэвлэсэн: (2010)

Epistatic interactions between genetic disorders of hemoglobin can explain why the sickle-cell gene is uncommon in the Mediterranean
-н: Penman, B, зэрэг
Хэвлэсэн: (2009)

Epistatic interactions between genetic disorders of hemoglobin can explain why the sickle-cell gene is uncommon in the Mediterranean.
-н: Penman, B, зэрэг
Хэвлэсэн: (2009)

Influenza outbreaks
-н: Wikramaratna, P, зэрэг
Хэвлэсэн: (2009)

Influenza outbreaks.
-н: Wikramaratna, P, зэрэг
Хэвлэсэн: (2009)

Targeting innate immunity to downmodulate adaptive immunity and reverse type 1 diabetes
-н: Itoh A, зэрэг
Хэвлэсэн: (2017-05-01)

A naturally protective epitope of limited variability as an influenza vaccine target
-н: Thompson, C, зэрэг
Хэвлэсэн: (2018)

Understanding the contrasting spatial haplotype patterns of malaria-protective β-globin polymorphisms
-н: Hockham, C, зэрэг
Хэвлэсэн: (2015)

Guest editorial: understanding dental pulp innate immunity - a basis for identifying new targets for therapeutic agents that dampen inflammation
-н: Jean-Christophe Farges
Хэвлэсэн: (2009-06-01)

Estimating the false-negative test probability of SARS-CoV-2 by RT-PCR
-н: Wikramaratna, PS, зэрэг
Хэвлэсэн: (2020)

Prediction of thioredoxin and glutaredoxin target proteins by identifying reversibly oxidized cysteinyl residues
-н: Lee Hang-mao, зэрэг
Хэвлэсэн: (2010-12-01)

In vivo inducible reverse genetics in patients’ tumors to identify individual therapeutic targets
-н: Michela Carlet, зэрэг
Хэвлэсэн: (2021-09-01)

The evolution of viral diversity
-н: Wikramaratna, P
Хэвлэсэн: (2012)

A naturally protective epitope of limited variability as an influenza vaccine target
-н: Craig P. Thompson, зэрэг
Хэвлэсэн: (2018-09-01)

From Renal Biomarkers to Therapeutic Targets: The Use of Monocyte Chemoattractant Protein 1, Transforming Growth Factor-Beta, and Connective Tissue Growth Factor in Diabetic Nephropathy and Antineutrophil Cytoplasmic Antibody-Associated Vasculitis
-н: Katrina J Spensley, зэрэг
Хэвлэсэн: (2018-12-01)

Protective antigens against glanders identified by expression library immunization
-н: Gregory C. Whitlock, зэрэг
Хэвлэсэн: (2011-11-01)

High-Throughput Antibody Profiling Identifies Targets of Protective Immunity against <i>P. falciparum</i> Malaria in Thailand
-н: Ifra Hassan, зэрэг
Хэвлэсэн: (2023-08-01)

A reverse vaccinology approach identifies putative vaccination targets in the zoonotic nematode Ascaris
-н: Francisco M. D. Evangelista, зэрэг
Хэвлэсэн: (2022-11-01)

The antigenic evolution of influenza: drift or thrift?
-н: Wikramaratna, P, зэрэг
Хэвлэсэн: (2013)

The effects of tertiary and quaternary infections on the epidemiology of dengue.
-н: Wikramaratna, P, зэрэг
Хэвлэсэн: (2010)

The antigenic evolution of influenza: drift or thrift?
-н: Wikramaratna, P, зэрэг
Хэвлэсэн: (2013)

Identifying asynchronies: Reverse trigger
-н: Víctor Perez, зэрэг
Хэвлэсэн: (2022-06-01)

Sirtuin1 Targeting Reverses Innate and Adaptive Immune Tolerance in Septic Mice
-н: Ayana N. Martin, зэрэг
Хэвлэсэн: (2018-01-01)

Targeting Cancer Cell Ferroptosis to Reverse Immune Checkpoint Inhibitor Therapy Resistance
-н: Jingjing Deng, зэрэг
Хэвлэсэн: (2022-03-01)

Proteomic analysis of Kveim reagent identifies targets of cellular immunity in sarcoidosis
-н: Eberhardt, C, зэрэг
Хэвлэсэн: (2017)

Adaptive immunity selects against malaria infection blocking mutations.
-н: Bridget S Penman, зэрэг
Хэвлэсэн: (2020-10-01)