Cytotoxic T-cell activity antagonized by naturally occurring HIV-1 Gag variants.
Most asymptomatic individuals infected with HIV-1 have a cytotoxic T lymphocyte (CTL) response to the virus Gag proteins which can be demonstrated in vitro. Epitopes have been mapped in p17 Gag and p24 Gag restricted by HLA-B8 (p17-3 and p24-13) and -B27 (p24-14). Viruses isolated from patients who...
Main Authors: | Klenerman, P, Rowland-Jones, S, McAdam, S, Edwards, J, Daenke, S, Lalloo, D, Köppe, B, Rosenberg, W, Boyd, D, Edwards, A |
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Format: | Journal article |
Language: | English |
Published: |
1994
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