Structure and function of CYP108D1 from Novosphingobium aromaticivorans DSM12444: an aromatic hydrocarbon-binding P450 enzyme.

Structure and function of CYP108D1 from Novosphingobium aromaticivorans DSM12444: an aromatic hydrocarbon-binding P450 enzyme.

Show other versions (1)

CYP108D1 from Novosphingobium aromaticivorans DSM12444 binds a range of aromatic hydrocarbons such as phenanthrene, biphenyl and phenylcyclohexane. Its structure, which is reported here at 2.2 Å resolution, is closely related to that of CYP108A1 (P450terp), an α-terpineol-oxidizing enzyme. The compo...

Full description

Bibliographic Details
Main Authors:	Bell, S, Yang, W, Yorke, J, Zhou, W, Wang, H, Harmer, J, Copley, R, Zhang, A, Zhou, R, Bartlam, M, Rao, Z, Wong, L
Format:	Journal article
Language:	English
Published:	2012

Similar Items

Structure and function of CYP108D1 from Novosphingobium aromaticivorans DSM12444: An aromatic hydrocarbon-binding P450 enzyme
by: Bell, S, et al.
Published: (2012)

Structural Analysis of CYP101C1 from Novosphingobium aromaticivorans DSM12444.
by: Ma, M, et al.
Published: (2011)

Molecular characterization of a class I P450 electron transfer system from Novosphingobium aromaticivorans DSM12444.
by: Yang, W, et al.
Published: (2010)

Crystallization and preliminary X-ray analysis of CYP153C1 from Novosphingobium aromaticivorans DSM12444.
by: Zhou, R, et al.
Published: (2011)

Purification, crystallization and preliminary X-ray analysis of cytochrome P450 219A1 from Novosphingobium aromaticivorans DSM 12444.
by: Hong, C, et al.
Published: (2009)

P450 enzymes from the bacterium Novosphingobium aromaticivorans.
by: Bell, S, et al.
Published: (2007)

A cytochrome P450 class I electron transfer system from Novosphingobium aromaticivorans.
by: Bell, S, et al.
Published: (2010)

iNovo479: Metabolic Modeling Provides a Roadmap to Optimize Bioproduct Yield from Deconstructed Lignin Aromatics by <i>Novosphingobium aromaticivorans</i>
by: Alexandra M. Linz, et al.
Published: (2022-04-01)

Biodegradation of polycyclic aromatic hydrocarbons by Novosphingobium pentaromativorans US6-1.
by: Yihua Lyu, et al.
Published: (2014-01-01)

Correction: Biodegradation of Polycyclic Aromatic Hydrocarbons by Novosphingobium pentaromativorans US6-1
Published: (2014-01-01)

Structure, electronic properties and catalytic behaviour of an activity-enhancing CYP102A1 (P450(BM3)) variant.
by: Whitehouse, C, et al.
Published: (2011)

Protein engineering of cytochrome p450(cam) (CYP101) for the oxidation of polycyclic aromatic hydrocarbons.
by: Harford-Cross, C, et al.
Published: (2000)

A highly active single-mutation variant of P450BM3 (CYP102A1).
by: Whitehouse, C, et al.
Published: (2009)

Structural basis for the properties of two single-site proline mutants of CYP102A1 (P450BM3).
by: Whitehouse, C, et al.
Published: (2010)

Proteomic characterization of plasmid pLA1 for biodegradation of polycyclic aromatic hydrocarbons in the marine bacterium, Novosphingobium pentaromativorans US6-1.
by: Sung Ho Yun, et al.
Published: (2014-01-01)

Engineering P450s by Rational Design
by: Wong, L, et al.
Published: (2010)

Polycyclic aromatic hydrocarbons and cytochrome P450 in HIV pathogenesis
by: Paluri Sai Shantanu eRao, et al.
Published: (2015-06-01)

The dynamics of camphor in the cytochrome P450 CYP101D2.
by: Vohra, S, et al.
Published: (2013)

Caulobacter and Novosphingobium in tumor tissues are associated with colorectal cancer outcomes
by: Bin Zhou, et al.
Published: (2023-01-01)

Attenuation of Polycyclic Aromatic Hydrocarbon (PAH)-Mediated Pulmonary DNA Adducts and Cytochrome P450 (CYP)1B1 by Dietary Antioxidants, Omega-3 Fatty Acids, in Mice
by: Guodong Zhou, et al.
Published: (2022-01-01)

Protein engineering of Bacillus megaterium CYP102. The oxidation of polycyclic aromatic hydrocarbons.
by: Carmichael, AB, et al.
Published: (2001)

Crystal structure of CYP199A2, a para-substituted benzoic acid oxidizing cytochrome P450 from Rhodopseudomonas palustris.
by: Bell, S, et al.
Published: (2008)

Protein recognition in ferredoxin-P450 electron transfer in the class I CYP199A2 system from Rhodopseudomonas palustris.
by: Bell, S, et al.
Published: (2010)

A fungal P450 (CYP5136A3) capable of oxidizing polycyclic aromatic hydrocarbons and endocrine disrupting alkylphenols: role of Trp(129) and Leu(324).
by: Khajamohiddin Syed, et al.
Published: (2011-01-01)

Chain length-dependent cooperativity in fatty acid binding and oxidation by cytochrome P450BM3 (CYP102A1).
by: Rowlatt, B, et al.
Published: (2011)

Improved oxidation of aromatic and aliphatic hydrocarbons using rate enhancing variants of P450Bm3 in combination with decoy molecules
by: Munday, S, et al.
Published: (2015)

Effects of Avitinib on CYP450 Enzyme Activity in vitro and in vivo in Rats
by: Shi Y, et al.
Published: (2021-08-01)

Regioselective oxidation of heterocyclic aromatic hydrocarbons catalyzed by cytochrome P450: A case study of carbazole
by: Zexi Hou, et al.
Published: (2023-06-01)

Transcriptome profiling of Paraburkholderia aromaticivorans AR20-38 during ferulic acid bioconversion
by: Caroline Poyntner, et al.
Published: (2022-11-01)

Isolation of Pseudomonas aromaticivorans sp. nov from a hydrocarbon-contaminated groundwater capable of degrading benzene-, toluene-, m- and p-xylene under microaerobic conditions
by: Sinchan Banerjee, et al.
Published: (2022-09-01)

P450(BM3) (CYP102A1): connecting the dots.
by: Whitehouse, C, et al.
Published: (2012)

Phylogenetic analysis of the cytochrome P450 (CYP450) nucleotide sequences of the horse and predicted CYP450s of the white rhinoceros (Ceratotherium simum) and other mammalian species
by: Marion Leiberich, et al.
Published: (2018-10-01)

Drug oxidation by Cytochrome P450BM3: metabolite synthesis and discovering new P450 reaction types
by: Ren, X, et al.
Published: (2015)

The structure of CYP101D2 unveils a potential path for substrate entry into the active site.
by: Yang, W, et al.
Published: (2011)

The MrCYP52 cytochrome P450 monoxygenase gene of Metarhizium robertsii is important for utilizing insect epicuticular hydrocarbons.
by: Liangcai Lin, et al.
Published: (2011-01-01)

Desaturation of alkylbenzenes by cytochrome P450(BM3) (CYP102A1).
by: Whitehouse, C, et al.
Published: (2008)

Whole genome-scale assessment of gene fitness of Novosphingobium aromaticavorans during spaceflight
by: Gayatri Sharma, et al.
Published: (2023-12-01)

Unraveling the 17β-Estradiol Degradation Pathway in Novosphingobium tardaugens NBRC 16725
by: Juan Ibero, et al.
Published: (2020-12-01)

Identification and analysis of CYP450 genes from transcriptome of Lonicera japonica and expression analysis of chlorogenic acid biosynthesis related CYP450s
by: Xiwu Qi, et al.
Published: (2017-09-01)

Dearomatisation of o-xylene by P450BM3 (CYP102A1).
by: Whitehouse, C, et al.
Published: (2011)