Synthesis of (+)-obtusenyne.
An enantioselective synthesis of the halogenated medium-ring ether natural product (+)-obtusenyne is reported which uses the ring expansion of a seven-membered ketene acetal by means of a Claisen rearrangement to construct the core nine-membered oxygen heterocycle. The trans substituents across the...
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Bibliographic Details
Main Authors: |
Mak, S,
Curtis, N,
Payne, A,
Congreve, MS,
Wildsmith, A,
Francis, C,
Davies, J,
Pascu, S,
Burton, J,
Holmes, AB |
Format: | Journal article
|
Language: | English |
Published: |
2008
|