Repeat doses of antibody to serum amyloid P component clear amyloid deposits in patients with systemic amyloidosis.

Repeat doses of antibody to serum amyloid P component clear amyloid deposits in patients with systemic amyloidosis.

Systemic amyloidosis is a fatal disorder caused by pathological extracellular deposits of amyloid fibrils that are always coated with the normal plasma protein, serum amyloid P component (SAP). The small-molecule drug, miridesap, [(R)-1-[6-[(R)-2-carboxy-pyrrolidin-1-yl]-6-oxo-hexanoyl]pyrrolidine-2...

書目詳細資料
Main Authors:	Richards, D, Cookson, L, Barton, S, Liefaard, L, Lane, T, Hutt, D, Ritter, J, Fontana, M, Moon, J, Gillmore, J, Wechalekar, A, Hawkins, P, Pepys, M
格式:	Journal article
語言:	English
出版:	American Association for the Advancement of Science 2018

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