The Apcl323t/+ mouse: A novel murine model analagous to the APC-1309 mutation causing severe intestinal polyposis in humans

Geahča maid

• The APC1310T/+ mouse: A novel murine model of intestinal tumorigenesis analogous to the APC-1309 mutation causing severe intestinal polyposis in humans
  Dahkki: Deheragoda, MG, et al.
  Almmustuhtton: (2007)
• The Apc 1322T mouse develops severe polyposis associated with submaximal nuclear beta-catenin expression.
  Dahkki: Pollard, P, et al.
  Almmustuhtton: (2009)
• Severe polyposis in Apc1322T mice is associated with submaximal Wnt signalling and increased expression of the stem cell marker Lgr5
  Dahkki: Lewis, A, et al.
  Almmustuhtton: (2010)
• Severe polyposis in Apc(1322T) mice is associated with submaximal Wnt signalling and increased expression of the stem cell marker Lgr5.
  Dahkki: Lewis, A, et al.
  Almmustuhtton: (2010)
• The C-terminus of Apc does not influence intestinal adenoma development or progression
  Dahkki: Lewis, A, et al.
  Almmustuhtton: (2012)