Antibodies expose multiple weaknesses in the glycan shield of HIV.

A shield of glycans coat the viral envelope proteins of the human immunodeficiency virus (HIV). Broadly neutralising antibodies can recognise this shield despite structural variation in these ‘self’ carbohydrate structures.

Bibliografske podrobnosti
Main Authors: Crispin, M, Bowden, T
Format: Journal article
Jezik:English
Izdano: Nature Publishing Group 2013
Opis
Izvleček:A shield of glycans coat the viral envelope proteins of the human immunodeficiency virus (HIV). Broadly neutralising antibodies can recognise this shield despite structural variation in these ‘self’ carbohydrate structures.